Decisions about deep brain stimulation therapy in Parkinson’s disease

Author:

Brandão Pedro1,Grippe Talyta Cortez2,Modesto Luiz Cláudio2,Ferreira André Gustavo Fonseca2,Silva Flávia Martins da2,Pereira Flávio Faria2,Lobo Marcelo Evangelista2,Allam Nasser3,Freitas Tiago da Silva2,Munhoz Renato P.4

Affiliation:

1. Universidade de Brasília, Brasil; Câmara dos Deputados, Brasil

2. Hospital de Base do Distrito Federal, Brasil

3. Universidade de Brasília, Brasil; Hospital de Base do Distrito Federal, Brasil

4. University of Toronto, Canada

Abstract

ABSTRACT Parkinson’s disease can be treated surgically in patients who present with motor complications such as fluctuations and dyskinesias, or medically-refractory disabling tremor. In this review, a group of specialists formulated suggestions for a preoperative evaluation protocol after reviewing the literature published up to October 2017. In this protocol, eligibility and ineligibility criteria for surgical treatment were suggested, as well as procedures that should be carried out before the multidisciplinary therapeutic decisions. The review emphasizes the need to establish “DBS teams”, with professionals dedicated specifically to this area. Finally, surgical target selection (subthalamic nucleus or globus pallidus internus) is discussed briefly, weighing the pros and cons of each target.

Publisher

FapUNIFESP (SciELO)

Subject

Neurology,Neurology (clinical)

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