Affiliation:
1. University of Modena and Reggio Emilia, Italy
2. NOVA University of Lisbon, Portugal
Abstract
ABSTRACT Objective: To gain a better understanding of how long-acting injectable antipsychotic (LAI) therapy is perceived by patients. Methods: A search for qualitative studies has been carried out on PubMed, Google Scholar, PsycINFO and PsycArticles, yielding 11 studies suitable for a review of qualitative studies. The reporting approach chosen was meta-ethnography, following the ENTREQ statement recommendations. Key concepts common to the different studies were extrapolated and then analysed in a systematic and comparative way. Results: Some recurrent issues were associated with LAIs, such as fear of coercion, fear of needles and lack of knowledge about depot therapy. These topics are linked to each other and the patients most concerned about the disadvantages of LAIs are those who are less informed about them, or who have experienced coercion and trauma during hospitalisation. On the other hand, patients who had already received LAIs, and those who had a good therapeutic relationship with their healthcare providers expressed satisfaction with this form of treatment and its continuation. Conclusion: Long-acting injectable antipsychotics are a tool in the management of mental disorders, and a viable alternative to oral medication. Patients show curiosity towards this method of administration, but lack of knowledge is a common finding. Shared decision making about the use of LAIs antipsychotics requires that patients receive accurate information and support for their decision regarding medication.
Subject
Psychiatry and Mental health
Reference43 articles.
1. Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017;James SL;The Lancet. Elsevier,2018
2. Attitudes towards long–acting depot antipsychotics: a survey of patients, relatives and psychiatrists;Jaeger M;Psychiatry Res,2010
3. Antipsychotic Adherence Over Time Among Patients Receiving Treatment for Schizophrenia: A Retrospective Review;Valenstein M;J Clin Psychiatry,2006
4. Prevalence of and risk factors for medication nonadherence in patients with schizophrenia: a comprehensive review of recent literature;Lacro JP;J Clin Psychiatry,2002
5. Antipsychotic medication adherence in schizophrenia;Byerly MJ;Psychiatr Clin North Am,2007