Toxoplasma gondii infection of the central nervous system and suicide: A case-control study of decedents-Reference-Cited by-同舟云学术

Toxoplasma gondii infection of the central nervous system and suicide: A case-control study of decedents

Published:2023-11-23 Issue:3 Volume:13 Page:77-82
ISSN:2062-509X
Container-title:European Journal of Microbiology and Immunology
language:
Short-container-title:EuJMI

Author:

Mendoza-Larios Laura Alejandra¹,García-Dolores Fernando¹,Sánchez-Anguiano Luis Francisco²,Antuna-Salcido Elizabeth Irasema³,Hernández-Tinoco Jesús²,Rocha-Salais Adriana²,Segoviano-Mendoza Marcela Araceli⁴,Sifuentes-Álvarez Antonio²,Alvarado-Esquivel Cosme²^ORCID

Affiliation:

1. Instituto de Ciencias Forenses de la Ciudad de México, Avenida Niños Héroes 130, Colonia Doctores, Delegación Cuauhtémoc, 06720 Ciudad de México, Mexico

2. Biomedical Research Laboratory, Faculty of Medicine and Nutrition, Juárez University of Durango State, Avenida Universidad S/N. 34000 Durango, Mexico

3. Institute for Scientific Research “Dr. Roberto Rivera Damm”, Juárez University of Durango State, Avenida Universidad S/N, 34000 Durango, Mexico

4. Department of Microbiology, Faculty of Medicine and Nutrition, Juárez University of Durango State, Avenida Universidad S/N. 34000 Durango, Mexico

Abstract

AbstractWe sought to determine the association between Toxoplasma gondii (T. gondii) infection of the central nervous system and suicide in a sample of decedents in Mexico City. One hundred and forty-seven decedents (87 who committed suicide and 60 who did not commit suicide) were studied. Brain tissues (amygdala and prefrontal cortex) of decedents were examined for the detection of T. gondii using immunohistochemistry. Detection of T. gondii was positive in 7 (8.0%) of the 87 cases (6 found in prefrontal cortex and one in amygdala), and in one (1.7%) of the 60 controls (found in prefrontal cortex) (OR: 5.16; 95% CI: 0.61–43.10; P = 0.14). Results suggest that T. gondii infection in brain is not associated with suicide. Further studies to confirm this finding are needed.

Publisher

Akademiai Kiado Zrt.

Subject

Applied Mathematics,General Mathematics

Link

https://akjournals.com/downloadpdf/journals/1886/13/3/article-p77.xml

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