EVALUATION OF CEREBRAL PERFUSION AND CEREBRAL HEMODYNAMICS CHANGES IN PATIENTS WITH SYMPTOMATIC CAROTID ARTERY STENOSIS BEFORE AND AFTER STENTING BY DSA PARAMETRIC IMAGING

HUAJUN BA^1,3, QUN LIN³, JIANYONG CAI³, CHUAN LU³, JUN SUN³, LIANTING MA²

¹Southern Medical University, No. 1023, Shatai Nan Road, Guangzhou, 510515, China - ²Department of Neurosurgery, Wuhan general hospital of Guangzhou Military Command affiliated to Southern Medical University, No. 627, Wuluo Road, Wuhan, 430070, China - ³Department of Neurosurgery, Wenzhou Central Hospital, No. 32, Dajian Road, Wenzhou, 325000, China

Objective: Investigating the DSA parametric imaging’s value of application in evaluating the changes of cerebral perfusion and cerebral hemodynamics changes before and after stenting in subjects having symptomatic carotid artery stenosis.

Patients and methods: From March 2006 to March 2017, 30 patients admitted to our hospital with unilateral carotid artery bifurcation stenosis were selected as the subjects. After stenting treatment, the effect of carotid artery stenting on intracranial blood flow was quantitatively evaluated according to the comparisons before and after stenting by using the iFLOW post processing techni- que with DSA scan.

Results: After operation, the brain peak value and the max slope rates of time - gray scale curves of ipsilateral operation in brain of the subjects were considerably more when compared to those prior to operation (P<0.05), and the time to peak, mean transit time and circulation time of ipsilateral operation were significantly decreased (P<0.05). After operation, the peak value, time of appearance of peak, the time to peak, mean transit time and circulation time of contralateral operation in brain of patients were significantly higher than those of before operation, and there was a considerable variation with probability less than 0.01. After ope- ration, the peak value of posterior circulation was considerably less compared to that before operation with probability less than 0.05, however, the time of appearance of peak, the time to peak, mean transit time and circulation time were significantly higher than before operation, the difference was significant (P<0.05).

Conclusion: The evaluation of cerebral hemodynamics changes after stenting, by using the post processing function of iFLOW, according to the quantitative comparison of blood flow velocity in the same part of intracranial vessels before and after operation, is accurate and reliable.