Evaluation of Brucellosis Vaccines: A Comprehensive Review

Author:

Heidary Mohsen,Dashtbin Shirin,Ghanavati Roya,Mahdizade Ari Marzie,Bostanghadiri Narjess,Darbandi Atieh,Navidifar Tahereh,Talebi Malihe

Abstract

Brucellosis is a bacterial zoonosis caused by Brucella spp. which can lead to heavy economic losses and severe human diseases. Thus, controlling brucellosis is very important. Due to humans easily gaining brucellosis from animals, animal brucellosis control programs can help the eradication of human brucellosis. There are two popular vaccines against animal brucellosis. Live attenuated Brucella abortus strain 19 (S19 vaccine) is the first effective and most extensively used vaccine for the prevention of brucellosis in cattle. Live attenuated Brucella melitensis strain Rev.1 (Rev.1 vaccine) is the most effective vaccine against caprine and ovine brucellosis. Although these two vaccines provide good immunity for animals against brucellosis, the expense of persistent serological responses is one of the main problems of both vaccines. The advantages and limitations of Brucella vaccines, especially new vaccine candidates, have been less studied. In addition, there is an urgent need for new strategies to control and eradicate this disease. Therefore, this narrative review aims to present an updated overview of the available different types of brucellosis vaccines.

Publisher

Frontiers Media SA

Subject

General Veterinary

Reference172 articles.

1. Brucellosis: a worldwide zoonosis;Boschiroli;Curr Opin Microbiol.,2001

2. The use of live vaccine for vaccination of human beings against brucellosis in the USSR;Vershilova;Bull World Health Organ.,1961

3. The changing Brucella ecology: novel reservoirs, new threats;Pappas;Int J Antimicrob Agents.,2010

4. OIE manual of diagnostic tests and vaccines for terrestrial animals (mammals, birds and bees) 5th edn. Volumes 1 & 2. World Organization for Animal Health 2004. ISBN 92 9044 622 6.80 140;Stear;Parasitology,2005

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3