Applications of linking PBPK and PD models to predict the impact of genotypic variability, formulation differences, differences in target binding capacity and target site drug concentrations on drug responses and variability-Reference-Cited by-同舟云学术

Applications of linking PBPK and PD models to predict the impact of genotypic variability, formulation differences, differences in target binding capacity and target site drug concentrations on drug responses and variability

Published:2014-11-26 Issue: Volume:5 Page:
ISSN:1663-9812
Container-title:Frontiers in Pharmacology
language:
Short-container-title:Front. Pharmacol.

Author:

Chetty Manoranjenni,Rose Rachel H.,Abduljalil Khaled,Patel Nikunjkumar,Lu Gaohua,Cain Theresa,Jamei Masoud,Rostami-Hodjegan Amin

Publisher

Frontiers Media SA

Subject

Pharmacology (medical),Pharmacology

Reference50 articles.

1. The QT interval.;Bednar;Prog. Cardiovasc. Dis.,2001

2. Greater quinidine-induced qtc interval prolongation in women.;Benton;Clin. Pharmacol. Ther.,2000

3. Operational models of pharmacological agonism.;Black;Proc. R. Soc. Lond. B Biol. Sci.,1983

4. Formulation of long-acting nifedipine tablets influences the heart rate and sympathetic nervous system response in hypertensive patients.;Brown;Br. J. Clin. Pharmacol.,2008

5. Application of IVIVE and PBPK modeling in prospective prediction of clinical pharmacokinetics: strategy and approach during the drug discovery phase with four case studies.;Chen;Biopharm. Drug Dispos.,2012

Cited by 49 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Can 3D Printed Tablets Be Bioequivalent and How to Test It: A PBPK Model Based Virtual Bioequivalence Study for Ropinirole Modified Release Tablets;Pharmaceutics;2024-02-09

2. Physiologically-Based Pharmacokinetic Modeling for Drugs Cleared by Non-Cytochrome P450 Enzymes: State-of-the-Art and Future Perspectives;Drug Metabolism and Disposition;2023-10-25

3. Computational Modeling of Drug Oral Bioavailability;Oral Bioavailability and Drug Delivery;2023-10-10

4. Physiologically Based Pharmacokinetic Model To Predict Metoprolol Disposition in Healthy and Disease Populations;ACS Omega;2023-08-03

5. Physiologically‐based pharmacokinetic modeling of quinidine to establish a CYP3A4, P‐gp, and CYP2D6 drug–drug–gene interaction network;CPT: Pharmacometrics & Systems Pharmacology;2023-05-23