Embracing the Diversity of Halogen Bonding Motifs in Fragment-Based Drug Discovery—Construction of a Diversity-Optimized Halogen-Enriched Fragment Library-Reference-Cited by-同舟云学术

Embracing the Diversity of Halogen Bonding Motifs in Fragment-Based Drug Discovery—Construction of a Diversity-Optimized Halogen-Enriched Fragment Library

Published:2019-02-18 Issue: Volume:7 Page:
ISSN:2296-2646
Container-title:Frontiers in Chemistry
language:
Short-container-title:Front. Chem.

Author:

Heidrich Johannes,Sperl Laura E.,Boeckler Frank M.

Publisher

Frontiers Media SA

Subject

General Chemistry

Reference73 articles.

1. Two- and three-dimensional rings in drugs;Aldeghi;Chem. Biol. Drug Des.,2013

2. Revisiting the general solubility equation: in silico prediction of aqueous solubility incorporating the effect of topographical polar surface area;Ali;J. Chem. Inform. Model.,2012

3. Identification of diverse database subsets using property-based and fragment-based molecular descriptions;Ashton;Quan. Struct. Activity Relationships,2002

4. Proteome-wide covalent ligand discovery in native biological systems;Backus;Nature,2016

5. Properties of atoms in molecules: atomic volumes;Bader;J. Am. Chem. Soc.,1987

Cited by 44 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Evaluation of a Covalent Library of Diverse Warheads (CovLib) Binding to JNK3, USP7, or p53;Drug Design, Development and Therapy;2024-07

2. High-confidence placement of low-occupancy fragments into electron density using the anomalous signal of sulfur and halogen atoms;Acta Crystallographica Section D Structural Biology;2024-06-01

3. A modular and synthetic biosynthesis platform for de novo production of diverse halogenated tryptophan-derived molecules;Nature Communications;2024-04-12

4. Iodinated 4,4’‐Bipyridines with Antiproliferative Activity Against Melanoma Cell Lines;ChemMedChem;2024-04-11

5. Polyhalogenated Carbohydrates: Synthesis and Applications of Sugar Halides from Fluorine to Iodine;European Journal of Organic Chemistry;2024-03-21