BIOCHEMICAL EFFECTS OF GINGER AND/OR GREEN TEA EXTRACTS IN HIGH FAT DIET - INDUCED OBESE RATS

Abstract

The current study was designed to clarify the sequel of administration of green tea and/ or extract of ginger on body weight, lipid profile, some hormones and some fertility variables in high fat diet (HFD) - induced obese rats. The results revealed that treatment of HFD obese rats with ginger extract decreased the elevated body weight (from 530+5.29 to 295+9.11), lee index (from 0.33±0.008 to 0.27±0.004), serum total cholesterol (from 25+2.57 to 187+2.79), triacylglycerol (TAG) (from 201+2.15 to154+1.82), low density lipoprotein cholesterol (LDL-C) (from 187.8+3.36 to119.6+2.31), very low density lipoprotein cholesterol (VLDL-C) (from 40.21+0.12 to 30.8+0.13), leptin (from 7.74+0.05 to 5.66+0.09), luetinzing hormone (LH) (from 0.30+0.006 to 0.19+0.005) and follicular stimulating hormone (FSH) (from 0.74+0.128 to 0.52+0.012) levels, but significantly elevated the decreased high density lipoprotein cholesterol (HDL-C) (from 21.40+0.50 to 36.40+0.81), serum testosterone (from 0.84+0.02 to 1.32+0.14), sperm count (from 44.20+2.08 to 65.20+0.54), motility (from 64+1.18 to 75.60+0.81) and normality (from 53.80+1.42 to 67+1.51). Similar results were observed with green tea treatment with minor variations. So, the inclusive outcomes may suggest that extracts of ginger and/ or green tea have a significant hypolipidemic effect with body weight reduction in rats fed high fat diet. In addition, the extracts may be qualified for ameliorative the ruined fertility parameters.