Timing of tumor-induced atelectasis resolution and pulmonary function restoration in the course of image-guided moderate hypofractionated thoracic irradiation: a case report and mini-review of literature-Reference-Cited by-同舟云学术

Timing of tumor-induced atelectasis resolution and pulmonary function restoration in the course of image-guided moderate hypofractionated thoracic irradiation: a case report and mini-review of literature

Published:2022-01-01 Issue:1 Volume:8 Page:
ISSN:2055-7159
Container-title:BJR|case reports
language:en
Short-container-title:BJR|case reports

Author:

Bodensohn Raphael¹^ORCID,Käsmann Lukas¹,Eze Chukwuka¹,Pazos Montserrat¹,Belka Claus¹²,Manapov Farkhad¹

Affiliation:

1. Department of Radiation Oncology, University Hospital, LMU Munich, Marchioninistraße 15, 81377 Munich, Germany

2. German Cancer Consortium (DKTK), Munich, Germany

Abstract

This case report describes a patient with squamous cell carcinoma of the lung (cT4 (Infiltration of left pulmonary artery) cN2 cM0, TNM eighth edition) and subsequent tumor-induced atelectasis of the left upper lobe. Despite initially presenting himself with a poor performance status (ECOG-PS III) and diminished lung function, the patient was treated with image-guided thoracic irradiation to a total dose of 45.0 Gy (to the whole planning target volume) / 52.5 Gy (as simultaneous integrated boost to the Primary Tumor) applied in 15 daily fractions. Through the radiation treatment, the upper lobe could be reaerated, and the patient’s lung function and performance were improved.

Publisher

British Institute of Radiology

Subject

Pharmacology (medical),Complementary and alternative medicine,Pharmaceutical Science

Link

https://www.birpublications.org/doi/pdf/10.1259/bjrcr.20200168

Reference10 articles.

1. Evaluation of Clinical Methods for Rating Dyspnea

2. Initial report on feasibility of PET/CT-based image-guided moderate hypofractionated thoracic irradiation in node-positive non-small cell lung Cancer patients with poor prognostic factors and strongly diminished lung function: a retrospective analysis

3. Moderate hypofractionated image-guided thoracic radiotherapy for locally advanced node-positive non-small cell lung cancer patients with very limited lung function: a case report

4. Effect of variations in atelectasis on tumor displacement during radiation therapy for locally advanced lung cancer

5. The response of atelectasis from lung cancer to radiation therapy