The role of immune mechanisms in the pathogenesis of hemorrhagic fever with renal syndrome-Reference-Cited by-同舟云学术

The role of immune mechanisms in the pathogenesis of hemorrhagic fever with renal syndrome

Published:2023-09-30 Issue:3 Volume:23 Page:4-12
ISSN:2410-3764
Container-title:Aspirantskiy Vestnik Povolzhiya
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Short-container-title:Aspirantskiy Vestnik Povolzhiya

Author:

Ivanov Mikhail F.^ORCID

Abstract

Hemorrhagic fever with renal syndrome (HFRS) is an acute natural focal disease of a viral nature. Its severity is determined by hemorrhagic phenomena, cytokine storm, kidney damage with the development of acute renal failure, and the possibility of death. HFRS is caused by viruses from the family Hantaviridae. Hantaviruses are characterized by the ability to infect endothelial and epithelial cells of the renal tubules, as well as innate immunity cells (neutrophils, monocytes, dendritic cells), which leads to both direct damage to the immune system and indirect through a violation of their functions. The review analyzes the immune mechanisms in HFRS and their role in the pathogenesis of this disease.

Publisher

Samara State Medical University

Link

https://aspvestnik.ru/2410-3764/article/viewFile/430418/pdf

Reference55 articles.

1. Hemorrhagic fever with renal syndrome: the challenge of our time

2. Hantavirus Reservoirs: Current Status with an Emphasis on Data from Brazil

3. Nikolskaya MV, Melnikov VL, Mitrofanova NN, et al. GLPS: epidemiological characteristics and dynamics of laboratory indicators. In: Proceedings of the XII International Scientific and Practical Conference "Innovative Science". M., 2018:19-25. (In Russ.). [Никольская М.В., Мельников В.Л., Митрофанова Н.Н., и др. ГЛПС: эпидемиологическая характеристика и динамика лабораторных показателей. В кн.: Материалы XII международной научно-практической конференции «Инновационная наука». М., 2018:19-25]. Available at: 3(12).pdf(nauchforum.ru)

4. Biodefense Implications of New-World Hantaviruses

5. Alekhin EK, Kamilov FKh, Khunafina DKh, et al. Hemorrhagic fever with renal syndrome. Medical Bulletin of Bashkortostan. 2013;5:24-31. (In Russ.). [Алехин Е.К., Камилов Ф.Х., Хунафина Д.Х., и др. Геморрагическая лихорадка с почечным синдромом. Медицинский вестник Башкортостана. 2013;5:24-31].