Thymus atlanticus: A Source of Nutrients with Numerous Health Benefits and Important Therapeutic Potential for Age-Related Diseases

Author:

El Midaoui Adil12,Khallouki Farid2,Couture Réjean1,Moldovan Florina3ORCID,Ismael Mahmoud Ali4,Ongali Brice1,Akoume Marie Yvonne3,Alem Chakib5,Ait Boughrous Ali2,Zennouhi Wafa2,Roqai Mhammed Chaoui6,Hajji Lhoussain7ORCID,Ghzaiel Imen8ORCID,Vejux Anne8ORCID,Lizard Gérard8ORCID

Affiliation:

1. Department of Pharmacology and Physiology, Faculty of Medicine, University of Montreal, Montreal, QC H3C 3J7, Canada

2. Department of Biology, Faculty of Sciences and Techniques, Errachidia, Moulay Ismail University of Meknes, Meknes 50050, Morocco

3. Research Center of CHU Sainte Justine, Faculty of Dentistry, Université de Montréal, Montreal, QC H3T 1J4, Canada

4. Northgate Centre 2074-9499 137 Ave NW, Edmonton, AB T5E 5R8, Canada

5. Research Team in Biochemistry and Natural Resources, Faculty of Sciences and Techniques, Moulay Ismail University of Meknes, Meknes 20250, Morocco

6. Ecole des Hautes Etudes de Biotechnologie et de Santé (EHEB), 183 Bd de la Résistance, Casablanca 20250, Morocco

7. Laboratory of Bioactives and Environmental Health, Faculty of Sciences, Moulay Ismail University, Meknes 50050, Morocco

8. Laboratory “Biochemistry of the Peroxisome, Inflammation and Lipid Metabolism”, Bio-peroxIL/EA7270, Université de Bourgogne/Inserm, 21000 Dijon, France

Abstract

Thymus atlanticus (Lamiaceae) is a plant endemic to the Mediterranean basin that is found in significant quantities in the arid regions of Morocco. Thymus atlanticus is used in traditional medicine to treat infectious and non-infectious diseases. It is also used for the isolation of essential oils and for the seasoning of many dishes in the Mediterranean diet. The major constituents of Thymus atlanticus are saponins, flavonoids, tannins, alkaloids, various simple and hydroxycinnamic phenolic compounds, and terpene compounds. Several of these compounds act on signaling pathways of oxidative stress, inflammation, and blood sugar, which are parameters often dysregulated during aging. Due to its physiochemical characteristics and biological activities, Thymus atlanticus could be used for the prevention and/or treatment of age-related diseases. These different aspects are treated in the present review, and we focused on phytochemistry and major age-related diseases: dyslipidemia, cardiovascular diseases, and type 2 diabetes.

Funder

Université de Bourgogne

Moulay Ismail University of Meknes

ABASIM

Publisher

MDPI AG

Subject

Food Science,Nutrition and Dietetics

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