Non-Squamous Cell Carcinoma of the Larynx: A State-of-the-Art Review

Author:

Chiesa-Estomba Carlos M.12,Barillari Maria Rosaria23ORCID,Mayo-Yáñez Miguel24ORCID,Maniaci Antonino25ORCID,Fakhry Nicolas26,Cammaroto Giovanni27ORCID,Ayad Tareck28,Lechien Jerome R.29ORCID

Affiliation:

1. Department of Otorhinolaryngology, Donostia University Hospital, Osakidetza, 20014 San Sebastian, Spain

2. Head & Neck Study Group, Young-Otolaryngologists of the International Federations of Oto-Rhino-Laryngological Societies (YO-IFOS), 13005 Marseille, France

3. Division of Phoniatrics and Audiology, Department of Mental and Physical Health and Preventive Medicine, University of L. Vanvitelli, 81100 Naples, Italy

4. Otorhinolaryngology—Head and Neck Surgery Department, Complexo Hospitalario Universitario A Coruña (CHUAC), 15006 A Coruña, Spain

5. Department of Medical and Surgical Sciences and Advanced Technologies “GF Ingrassia”, ENT Section, University of Catania, Via S. Sofia 78, 95125 Catania, Italy

6. Department of Otorhinolaryngology-Head and Neck Surgery, APHM, La Conception University Hospital, 13005 Marseille, France

7. Department of Otolaryngology—Head & Neck Surgery, Morgagni Pierantoni Hospital, 47100 Forli, Italy

8. Division of Otolaryngology—Head & Neck Surgery, Centre Hospitalier de L’Université de Montréal, Montreal, QC H2X 0C1, Canada

9. Department of Otolaryngology—Head & Neck Surgery, Foch Hospital, School of Medicine, UFR Simone Veil, Université Versailles Saint-Quentin-en-Yvelines (Paris Saclay University), 91190 Paris, France

Abstract

(1) Background: Non-squamous cell laryngeal carcinoma includes endothelial tumors, such as minor salivary gland tumors, lymphoepithelial tumors, neuroendocrine tumors, soft and hard tissue sarcomas, and malignant melanomas. (2) Methods: A state-of-the-art review using the MEDLINE/PUBMED, Google Scholar, Ovid Medline, Embase, and Scopus electronic databases was performed. (3) Conclusions: In order to optimize overall treatment outcomes, a multidisciplinary, patient-centered approach to the management of non-SCC of the larynx must be adopted universally; a national or international registry on non-SCC laryngeal cancer can be useful to improve understanding about the behavior of this kind of tumor.

Publisher

MDPI AG

Subject

Medicine (miscellaneous)

Reference100 articles.

1. Koroulakis, A., and Agarwal, M. (2022, December 12). Laryngeal Cancer, StatPearls [Internet], Available online: https://www.ncbi.nlm.nih.gov/books/NBK526076/.

2. American Cancer Society (2017). Cancer Facts & Figures 2017, American Cancer Society. Available online: https://www.cancer.org/content/dam/cancer-org/research/cancer-facts-and-statistics/annual-cancer-facts-andfigures/2017/cancer-facts-and-figures-2017.pdf.

3. American Cancer Society (2018). Cancer Facts & Figures 2018, American Cancer Society. Available online: https://www.cancer.org/content/dam/cancer-org/research/cancer-facts-and-statis-tics/annual-cancer-factsandfigures/2018/cancer-facts-and-figures-2018.pdf.

4. Patterns of care for cancer of the larynx in the United States;Shah;Arch. Otolaryngol. Head Neck Surg.,1997

5. Systemic therapy in non-conventional cancers of the larynx;Tan;Oral Oncol.,2018

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