Wide Use of Hyaluronic Acid in the Process of Wound Healing—A Rapid Review

Author:

Antoszewska Magdalena1ORCID,Sokolewicz Ewa Maria1ORCID,Barańska-Rybak Wioletta1

Affiliation:

1. Department of Dermatology, Venerology and Allergology, Medical University of Gdańsk, Debinki 7 Street, 80-952 Gdańsk, Poland

Abstract

Hyaluronic acid (HA), as one of the main components of the extracellular matrix (ECM), plays an important role in the process of wound-healing and tissue-repair processes due to its unique properties and different physiological functions. HA has an ability to maintain a moist environment that promotes healing, the stimulation of growth factors and cellular constituents, and the migration of various cells essential for healing. This paper offers a review of HA use in the process of wound healing, with emphasis on hard-to-heal wounds, and examines its various applications in ophthalmology and otorhinolaryngology. It proves HA to be a versatile agent which finds its use in various fields of medicine for its antioxidant, anti-inflammatory, antibacterial properties and accelerated wound healing.

Publisher

MDPI AG

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