Structural and Synthetic Aspects of Small Ring Oxa- and Aza-Heterocyclic Ring Systems as Antiviral Activities

Author:

Manna Sibasish1,Das Koushik1,Santra Sougata2,Nosova Emily V.23ORCID,Zyryanov Grigory V.23,Halder Sandipan1

Affiliation:

1. Department of Chemistry, Visvesvaraya National Institute of Technology, Nagpur 440010, India

2. Department of Organic and Biomolecular Chemistry, Chemical Engineering Institute, Ural Federal University, 19 Mira Street, 620002 Yekaterinburg, Russia

3. I. Ya. Postovskiy Institute of Organic Synthesis, Ural Division of the Russian Academy of Sciences, 22 S. Kovalevskoy Street, 620219 Yekaterinburg, Russia

Abstract

Antiviral properties of different oxa- and aza-heterocycles are identified and properly correlated with their structural features and discussed in this review article. The primary objective is to explore the activity of such ring systems as antiviral agents, as well as their synthetic routes and biological significance. Eventually, the structure–activity relationship (SAR) of the heterocyclic compounds, along with their salient characteristics are exhibited to build a suitable platform for medicinal chemists and biotechnologists. The synergistic conclusions are extremely important for the introduction of a newer tool for the future drug discovery program.

Funder

Science and Engineering Research Board

Publisher

MDPI AG

Subject

Virology,Infectious Diseases

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