Oxidative Stress and Natural Products in Orthodontic Treatment: A Systematic Review

Author:

Inchingolo Francesco1ORCID,Inchingolo Angelo Michele1ORCID,Latini Giulia1ORCID,Ferrante Laura1ORCID,Trilli Irma1ORCID,Del Vecchio Gaetano1ORCID,Palmieri Giulia1ORCID,Malcangi Giuseppina1ORCID,Inchingolo Alessio Danilo1ORCID,Dipalma Gianna1ORCID

Affiliation:

1. Interdisciplinary Department of Medicine, University of Bari “Aldo Moro”, 70124 Bari, Italy

Abstract

In recent years, orthodontics, a specialized branch of dentistry, has evolved considerably in terms of both techniques and materials used. Aimed at correcting dental malocclusions and craniofacial anomalies, it improves the functionality and aesthetics of the face and oral cavity. However, orthodontic treatment, in its developmental stages, may induce oxidative stress (O.S.) phenomena, with an increase in the production of reactive oxygen species (ROS), damaging the dental and periodontal tissues involved, affecting the short-, medium- and long-term results. Studies on the antioxidant effects of natural products (e.g., resveratrol, green tea, turmeric, etc.) in the medical field have aroused considerable interest in recent years. A systematic literature review was conducted on the PubMed, Scopus, and Web of Science databases using natural products (N.P.s), O.S., and orthodontic as keywords. The study aims to consider the determinants of the increase in ROS occurring during orthodontic treatment and the possibility of natural products being able to control and neutralize biochemical phenomena by restoring the physiological process in which the balance between the production of ROS and the ability of the body’s antioxidant system to neutralize them is in favor of the latter.

Publisher

MDPI AG

Subject

Food Science,Nutrition and Dietetics

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