Transient Stress Lymphocytosis in a Child: A Case Report and Systematic Review of the Literature

Author:

Placek Alexander1,Chan Randall Y.2ORCID,Vergara-Lluri Maria1ORCID,Brynes Russell K.1

Affiliation:

1. Hematopathology Section, Department of Pathology, University of Southern California Keck School of Medicine, Los Angeles, CA 90033, USA

2. Hematology-Oncology Division, Department of Pediatrics, University of Southern California Keck School of Medicine, Los Angeles, CA 90033, USA

Abstract

Transient stress lymphocytosis (TSL) is an under-recognized phenomenon associated with an acute stressful event such as physical trauma or various emergency medical conditions. Lymphocytosis generally resolves within several hours to days of the stressor. While most reports of TSL predominantly involve adult patients, it has only rarely been reported in pediatric patients. Here, we describe the clinical course of a 9-year-old male who developed TSL following a traumatic fall from a second-story balcony and provide a systematic literature review of TSL.

Publisher

MDPI AG

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3. Hoffman, R., and Benz, E.J. (2018). Lymphocytosis, lymphocytopenia, hypergammaglobulinemia, and hypogammaglobulinemia. Hematology: Basic Principles and Practice, Elsevier. [7th ed.].

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5. Transient stress lymphocytosis during crisis of sickle cell anemia and emergency trauma and medical conditions. An immunophenotyping study;Groom;Arch. Pathol. Lab. Med.,1990

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