Health-Promoting Activities and Associated Mechanisms of Polygonati Rhizoma Polysaccharides

Author:

Wang Shuzhen1,He Feng1,Wu Hongmei2,Xiang Fu1,Zheng Hongyan1,Wu Wei1,Li Shiming134ORCID

Affiliation:

1. College of Biology and Agricultural Resources, Huanggang Normal University, Huanggang 438000, China

2. Department of Library, Huanggang Normal University, Huanggang 438000, China

3. Misabel Group Inc., Shijiazhuang 051134, China

4. Department of Food Science, Rutgers University, New Brunswick, NJ 08901, USA

Abstract

Polygonati Rhizoma, a typical homology of medicine and food, possesses remarkable anti-fatigue, anti-aging, metabolic regulatory, immunomodulatory, anti-inflammatory, neuroprotective, anti-diabetes, and anti-cancer effects. Among bioactive phytochemicals in Polygonati Rhizoma, polysaccharides play important roles in the health-promoting activities through the mechanisms mentioned above and potential synergistic effects with other bioactives. In this review, we briefly introduce the updated biosynthesis of polysaccharides, the purification method, the structure characterization, and food applications, and discuss in detail the biological activities of Polygonati Rhizoma polysaccharides and associated mechanisms, aiming at broadening the usage of Polygonati Rhizoma as functional food and medicine.

Funder

Huanggang Science and Technology Bureau

Department of Science & Technology, Hebei Province for the Grant of International Collaboration for Model Enterprises of Misabel Group, Shijiazhuang, Hebei

Publisher

MDPI AG

Subject

Chemistry (miscellaneous),Analytical Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Molecular Medicine,Drug Discovery,Pharmaceutical Science

Reference150 articles.

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