Synthesis of Functionalized Azepines via Cu(I)-Catalyzed Tandem Amination/Cyclization Reaction of Fluorinated Allenynes-Reference-Cited by-同舟云学术

Synthesis of Functionalized Azepines via Cu(I)-Catalyzed Tandem Amination/Cyclization Reaction of Fluorinated Allenynes

Published:2022-08-15 Issue:16 Volume:27 Page:5195
ISSN:1420-3049
Container-title:Molecules
language:en
Short-container-title:Molecules

Author:

Philippova Anna N.,Vorobyeva Daria V.,Gribanov Pavel S.^ORCID,Godovikov Ivan A.,Osipov Sergey N.^ORCID

Abstract

An efficient method for the selective preparation of trifluoromethyl-substituted azepin-2-carboxylates and their phosphorous analogues has been developed via Cu(I)-catalyzed tandem amination/cyclization reaction of functionalized allenynes with primary and secondary amines.

Funder

Russian Foundation for Basic Research

Publisher

MDPI AG

Subject

Chemistry (miscellaneous),Analytical Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Molecular Medicine,Drug Discovery,Pharmaceutical Science

Link

https://www.mdpi.com/1420-3049/27/16/5195/pdf

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