Novel Derivatives of Nitrobenzofurazan with Chromogenic and Fluorogenic Properties

Author:

Bujor Alexandru1,Hanganu Anamaria12ORCID,Baratoiu Rodica3,Hristea Elena N.3,Tudose Madalina3ORCID,Tecuceanu Victorita2,Madalan Augustin M.1,Ionita Petre1ORCID

Affiliation:

1. Department of Inorganic, Organic Chemistry, Biochemistry and Catalysis, Faculty of Chemistry, University of Bucharest, 90 Panduri, 050663 Bucharest, Romania

2. Institute of Organic and Supramolecular Chemistry, Spl. Independentei 202B, 060023 Bucharest, Romania

3. Institute of Physical Chemistry, Spl. Independentei 202, 060023 Bucharest, Romania

Abstract

Five new derivatives were obtained utilizing 4-chloro-7-nitrobenzofurazan (NBD-chloride) in combination with furfurylamine, adamantylamine, aminohippuric acid, phenylalanine, and dehydroabietylamine. These derivatives were then subjected to a comparative analysis of their physical, chemical, and certain biological properties alongside two analogous and known compounds derived from the glycine and 4-amino-TEMPO free radical.

Funder

CSUD-UB

Publisher

MDPI AG

Subject

Chemistry (miscellaneous),Analytical Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Molecular Medicine,Drug Discovery,Pharmaceutical Science

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