Electrospun Nanofiber Scaffolds Loaded with Metal-Based Nanoparticles for Wound Healing

Author:

Dang Zheng1ORCID,Ma Xuemei1ORCID,Yang Zihao1,Wen Xiaohu1,Zhao Pengxiang1

Affiliation:

1. Faculty of Environment and Life, Beijing University of Technology, Beijing 100124, China

Abstract

Failures of wound healing have been a focus of research worldwide. With the continuous development of materials science, electrospun nanofiber scaffolds loaded with metal-based nanoparticles provide new ideas and methods for research into new tissue engineering materials due to their excellent antibacterial, anti-inflammatory, and wound healing abilities. In this review, the stages of extracellular matrix and wound healing, electrospun nanofiber scaffolds, metal-based nanoparticles, and metal-based nanoparticles supported by electrospun nanofiber scaffolds are reviewed, and their characteristics and applications are introduced. We discuss in detail the current research on wound healing of metal-based nanoparticles and electrospun nanofiber scaffolds loaded with metal-based nanoparticles, and we highlight the potential mechanisms and promising applications of these scaffolds for promoting wound healing.

Funder

Military Logistics Key Open Research Projects

National Natural Science Foundation of China

Sponsored by Beijing Nova Program

Publisher

MDPI AG

Subject

Polymers and Plastics,General Chemistry

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