The Million Veteran Program 1990–1991 Gulf War Era Survey: An Evaluation of Veteran Response, Characteristics, and Representativeness of the Gulf War Era Veteran Population

Author:

Harrington Kelly M.12ORCID,Quaden Rachel1,Steele Lea3,Helmer Drew A.45,Hauser Elizabeth R.67ORCID,Ahmed Sarah T.45ORCID,Aslan Mihaela89,Radhakrishnan Krishnan810ORCID,Honerlaw Jacqueline1,Nguyen Xuan-Mai T.11112ORCID,Muralidhar Sumitra13,Concato John914,Cho Kelly11215,Gaziano J. Michael11215,Whitbourne Stacey B.11215,

Affiliation:

1. Million Veteran Program (MVP) Coordinating Center, VA Boston Healthcare System, Boston, MA 02130, USA

2. Department of Psychiatry, Boston University Chobanian & Avedisian School of Medicine, Boston, MA 02118, USA

3. Veterans Health Research Program, Yudofsky Division of Neuropsychiatry, Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX 77030, USA

4. Center for Innovations in Quality, Effectiveness, and Safety (IQuESt), Michael E. DeBakey VA Medical Center, Houston, TX 77030, USA

5. Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA

6. VA Cooperative Studies Program Epidemiology Center-Durham, Department of Veterans Affairs, Durham, NC 27705, USA

7. Department of Biostatistics and Bioinformatics, Duke Molecular Physiology Institute, Duke University, Durham, NC 27705, USA

8. Cooperative Studies Program Clinical Epidemiology Research Center (CSP-CERC), VA Connecticut Healthcare System, West Haven, CT 06516, USA

9. Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06511, USA

10. National Mental Health and Substance Use Policy Laboratory, Substance Abuse and Mental Health Services Administration, Rockville, MD 20857, USA

11. Carle Illinois College of Medicine, University of Illinois, Champaign, IL 61820, USA

12. Department of Medicine, Harvard Medical School, Boston, MA 02115, USA

13. Office of Research and Development, Veterans Health Administration, Washington, DC 20420, USA

14. Food and Drug Administration, Silver Spring, MD 20993, USA

15. Division of Aging, Department of Medicine, Brigham and Women’s Hospital, Boston, MA 02115, USA

Abstract

To address gaps in understanding the pathophysiology of Gulf War Illness (GWI), the VA Million Veteran Program (MVP) developed and implemented a survey to MVP enrollees who served in the U.S. military during the 1990–1991 Persian Gulf War (GW). Eligible Veterans were invited via mail to complete a survey assessing health conditions as well as GW-specific deployment characteristics and exposures. We evaluated the representativeness of this GW-era cohort relative to the broader population by comparing demographic, military, and health characteristics between respondents and non-respondents, as well as with all GW-era Veterans who have used Veterans Health Administration (VHA) services and the full population of U.S. GW-deployed Veterans. A total of 109,976 MVP GW-era Veterans were invited to participate and 45,270 (41%) returned a completed survey. Respondents were 84% male, 72% White, 8% Hispanic, with a mean age of 61.6 years (SD = 8.5). Respondents were more likely to be older, White, married, better educated, slightly healthier, and have higher socioeconomic status than non-respondents, but reported similar medical conditions and comparable health status. Although generally similar to all GW-era Veterans using VHA services and the full population of U.S. GW Veterans, respondents included higher proportions of women and military officers, and were slightly older. In conclusion, sample characteristics of the MVP GW-era cohort can be considered generally representative of the broader GW-era Veteran population. The sample represents the largest research cohort of GW-era Veterans established to date and provides a uniquely valuable resource for conducting in-depth studies to evaluate health conditions affecting 1990–1991 GW-era Veterans.

Funder

VA Million Veteran Program

Office of Research and Development

U.S. Department of Veterans Affairs

VA Cooperative Studies Program Study

VA Health Services Research & Development

Publisher

MDPI AG

Subject

Health, Toxicology and Mutagenesis,Public Health, Environmental and Occupational Health

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