Meek Micro-Skin Grafting and Acellular Dermal Matrix in Pediatric Patients: A Novel Approach to Massive Extravasation Injury

Author:

Maruccia Michele1ORCID,Tedeschi Pasquale1ORCID,Corrao Claudia1,Elia Rossella1ORCID,La Padula Simone2ORCID,Di Summa Pietro G.3,Maggio Giulio M. M.1,Giudice Giuseppe1

Affiliation:

1. Division of Plastic and Reconstructive Surgery, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari Aldo Moro, Piazza Giulio Cesare, 70121 Bari, Italy

2. Department of Plastic and Reconstructive Surgery, Università degli Studi di Napoli Federico II, Via Pansini 5, 80131 Napoli, Italy

3. Department of Plastic and Hand Surgery, Centre Hospitalier Universitaire Vaudois (CHUV), University of Lausanne (UNIL), 1015 Lausanne, Switzerland

Abstract

(1) Background: Extravasation injuries in pediatric patients can lead to significant harm if they are not promptly diagnosed and treated. However, evidence-based standardization on extravasation management remains limited, particularly for extensive wound necrosis. This case report presents the management of an 8-week-old premature patient with an extensive extravasation injury involving the right forearm and dorsum of the hand. (2) Methods: The patient was evaluated by a multidisciplinary team in our Neonatal Intensive Care Unit. Surgical intervention involved the debridement of necrotic tissues, followed by temporary coverage with an acellular dermal matrix. Definitive coverage was achieved through Meek micrografting after three weeks. Physical therapy was provided with pre- and post-rehabilitation range of motion assessed using goniometric measurements. Scar quality was evaluated using the Vancouver Scar Scale. (3) Results: The engraftment rate of the Meek micrografts was 93%, with 16 out of 226 micrografts lost. The patient achieved a Vancouver Scar Scale score of 6, indicating a moderate degree of scarring. Significant improvements in elbow, wrist, and finger joint range of motion were observed at a 1-year follow-up. (4) Conclusions: Close observation and heightened awareness of extravasation risks by trained personnel are crucial. Meek micrografting combined with dermal substitute coverage represents an innovative approach to managing extravasation wounds in pediatric patients.

Publisher

MDPI AG

Subject

General Medicine

Reference29 articles.

1. Extravasation Injuries of the Limbs in Neonates and Children—Development of a Treatment Algorithm;Hackenberg;Dtsch. Arztebl. Int.,2021

2. Extravasation injuries on regional neonatal units;Wilkins;Arch. Dis. Child.-Fetal Neonatal Ed.,2004

3. Nonoperative management of full-thickness intravenous extravasation injuries in premature neonates using enzymatic debridement;Falcone;Ann. Plast. Surg.,1989

4. Facial skin breakdown in patients with non-invasive ventilation devices: Report of two cases and indications for treatment and prevention;Maruccia;Int. Wound J.,2015

5. Severe Extravasation Injuries in Neonates: A Report of 34 Cases;Kostogloudis;Pediatr. Dermatol.,2015

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