Current Methods for the Detection of Antibodies of Varicella-Zoster Virus: A Review

Author:

Pan Dequan1,Wang Wei1ORCID,Cheng Tong1ORCID

Affiliation:

1. State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Life Sciences, School of Public Health, Xiamen University, Xiamen 361102, China

Abstract

Infection with the varicella-zoster virus (VZV) causes chickenpox and shingles, which lead to significant morbidity and mortality globally. The detection of serum VZV-specific antibodies is important for the clinical diagnosis and sero-epidemiological research of VZV infection, and for assessing the effect of VZV vaccine immunization. Over recent decades, a variety of methods for VZV antibody detection have been developed. This review summarizes and compares the current methods for detecting VZV antibodies, and discussed future directions for this field.

Funder

National Natural Science Foundation of China

Publisher

MDPI AG

Subject

Virology,Microbiology (medical),Microbiology

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