Role of Overweight and Obesity in Gastrointestinal Disease

Author:

Emerenziani Sara,Pier Luca Guarino Michele,Trillo Asensio Laura,Altomare AnnamariaORCID,Ribolsi Mentore,Balestrieri Paola,Cicala MicheleORCID

Abstract

The prevalence of obesity is increasing worldwide, leading to a severe impairment of overall health. Actually, obesity has been associated with several pathological conditions, causing an excess overall mortality. In particular, overweight and obesity are well known risk factors for a variety of gastrointestinal (GI) disorders i.e., functional GI disorders as well as, inflammatory bowel disease (IBD), pancreatitis, and GI cancer. The aim of the present review is to summarize the potential role of overweight and obesity in GI disease with particular focus on plausible biological mechanisms that could explain the association between obesity and GI disease based on the most recent evidence in the literature.

Publisher

MDPI AG

Subject

Food Science,Nutrition and Dietetics

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