The Association of Vaccination for Common Adult Infectious Diseases and Uptake of COVID-19 Vaccines among 5,006,851 Veterans, 20 December 2020–31 October 2021

Author:

Bennett Brady W.1ORCID,Phillips Lawrence S.23,Gazmararian Julie A.1ORCID

Affiliation:

1. Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA 30322, USA

2. Atlanta VA Medical Center, Decatur, GA 30033, USA

3. Division of Endocrinology and Metabolism, Department of Medicine, School of Medicine, Emory University, Atlanta, GA 30322, USA

Abstract

Disparities in vaccination coverage for coronavirus disease 2019 (COVID-19) in the United States (U.S.) are consistent barriers limiting our ability to control the spread of disease, particularly those by age and race/ethnicity. This study examines the association between previous vaccination for common adult infectious diseases and vaccination for SARS-CoV-2 among a cohort of veterans in the U.S. Sociodemographic and clinical data were utilized from three databases within the Veterans Health Administration included in the electronic health record. We examined the association of previous vaccination for common adult vaccinations through six separate multivariable logistic regression analyses, one for each previous vaccine exposure, adjusting for demographic and clinical variables. We also examined the association of receiving any one of the six common adult vaccinations and vaccination against SARS-CoV-2. Adjusted models indicate higher odds of vaccination for SARS-CoV-2 among those who received each of the previous vaccinations. Significant differences were also noted by race/ethnicity and age. Veterans who recorded receiving any one of the previous vaccinations for common adult infections had significantly greater odds of receiving any vaccination against SARS-CoV-2. Understanding veterans’ previous vaccination status can assist researchers and clinicians in impacting the uptake of novel vaccines, such as vaccination against SARS-CoV-2.

Funder

National Center for Advancing Translational Sciences of the National Institutes of Health

VA awards CSP #2008

NIH

Cystic Fibrosis Foundation

Veterans Health Administration

Publisher

MDPI AG

Subject

Pharmacology (medical),Infectious Diseases,Drug Discovery,Pharmacology,Immunology

Reference38 articles.

1. Centers for Disease Control and Prevention (2022, August 20). COVID Data Tracker, Available online: https://covid.cdc.gov/covid-data-tracker/#vaccinations_vacc-people-additional-dose-totalpop.

2. Rentsch, C.T., Kidwai-Khan, F., Tate, J.P., Park, L.S., King, J.T., Skanderson, M., Hauser, R.G., Schultze, A., Jarvis, C.I., and Holodniy, M. (2020). Patterns of COVID-19 testing and mortality by race and ethnicity among United States veterans: A nationwide cohort study. PLoS Med., 17.

3. U.S. Department of Veterans Affairs (2024, January 17). About VHA. Veterans Health Administration, Available online: https://www.va.gov/health/aboutvha.asp#:~:text=The%20Veterans%20Health%20Admi.

4. U.S. Department of Veterans Affairs (2024, January 17). The Researcher’s Guide to VA Data. VA Information Research Center, Available online: https://virec.research.va.gov/Index.asp.

5. Souden, M. (2024, January 17). Overview of VA Data, Information Systems, National Databases and Research Use, Available online: https://www.hsrd.research.va.gov/for_researchers/cyber_seminars/archives/3694-notes.pdf.

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