Therapeutic Perspectives of Metal Nanoformulations

Author:

Islam Tawhida1ORCID,Rahaman Md. Mizanur1ORCID,Mia Md. Nayem1,Ara Iffat1,Islam Md. Tariqul1,Alam Riaz Thoufiqul23ORCID,Araújo Ana C. J.4,de Lima Silva João Marcos Ferreira5ORCID,de Lacerda Bruna Caroline Gonçalves Vasconcelos6,de Andrade Edlane Martins6ORCID,Khan Muhammad Ali1ORCID,Coutinho Henrique D. M.4ORCID,Husain Zakir1,Islam Muhammad Torequl1ORCID

Affiliation:

1. Department of Pharmacy, Bangabandhu Sheikh Mujibur Rahman Science and Technology University, Gopalganj 8100, Bangladesh

2. School of Medicine, Department of Medical Science, Jeonbuk National University, Jeonju 561-756, Republic of Korea

3. Nutrition and Immunology, Technical University Munich, 81675 Munich, Germany

4. Department of Biological Chemistry, Regional University of Cariri-URCA, Crato 63100-000, CE, Brazil

5. Department of Physical Education, Centro Universitário Doutor Leão Sampaio, Juazeiro do Norte 63024-015, CE, Brazil

6. CECAPE College, Av. Padre Cícero, 3917-São José, Juazeiro do Norte 63024-015, CE, Brazil

Abstract

In recent decades, acceptance of nanoparticles (NPs) in therapeutic applications has increased because of their outstanding physicochemical features. By overcoming the drawbacks of conventional therapy, the utilization of metal NPs, metal-oxide, or metal supported nanomaterials have shown to have significant therapeutic applications in medicine. This is proved by a lot of clinical and laboratory investigations that show improved treatment outcomes, site-specific drug delivery, and fewer side effects compared to traditional medicine. The metal NPs interaction with living cells (animal and plant) showed many ways to develop therapeutic models with the NPs. Despite all of the advancements that science has achieved, there is still a need to find out their performance for long-term use to solve modern challenges. In this regard, the present documentation reviews some potential metals, including silver (Ag), gold (Au), zinc (Zn), copper (Cu), iron (Fe), and nickel (Ni) NPs, as therapeutic agents in various areas such as anticancer, antimicrobial, antidiabetic, and applicable for the treatment of many other diseases. Depending on the outstanding ongoing research and practical trials, metal-based NPs can be considered the hope of prospective modern therapeutic areas.

Publisher

MDPI AG

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