Non-Thermal Plasma Treatment of Poly(tetrafluoroethylene) Dental Membranes and Its Effects on Cellular Adhesion-Reference-Cited by-同舟云学术

Non-Thermal Plasma Treatment of Poly(tetrafluoroethylene) Dental Membranes and Its Effects on Cellular Adhesion

Published:2023-10-10 Issue:20 Volume:16 Page:6633
ISSN:1996-1944
Container-title:Materials
language:en
Short-container-title:Materials

Author:

Nayak Vasudev Vivekanand¹^ORCID,Mirsky Nicholas Alexander¹^ORCID,Slavin Blaire V.¹^ORCID,Witek Lukasz²³⁴^ORCID,Coelho Paulo G.¹⁵,Tovar Nick²⁶

Affiliation:

1. Department of Biochemistry and Molecular Biology, Miller School of Medicine, University of Miami, Miami, FL 33136, USA

2. Biomaterials Division, College of Dentistry, New York University, New York, NY 10010, USA

3. Department of Biomedical Engineering, Tandon School of Engineering, New York University, 6 MetroTech Center, Brooklyn, NY 11201, USA

4. Hansjörg Wyss Department of Plastic Surgery, Grossman School of Medicine, New York University, New York, NY 10017, USA

5. DeWitt Daughtry Family Department of Surgery, Division of Plastic Surgery, Miller School of Medicine, University of Miami, Miami, FL 33136, USA

6. Department of Oral and Maxillofacial Surgery, New York University, Langone Medical Center and Bellevue Hospital Center, New York, NY 10016, USA

Abstract

Non-resorbable dental barrier membranes entail the risk of dehiscence due to their smooth and functionally inert surfaces. Non-thermal plasma (NTP) treatment has been shown to increase the hydrophilicity of a biomaterials and could thereby enhance cellular adhesion. This study aimed to elucidate the role of allyl alcohol NTP treatment of poly(tetrafluoroethylene) in its cellular adhesion. The materials (non-treated PTFE membranes (NTMem) and NTP-treated PTFE membranes (PTMem)) were subjected to characterization using scanning electron microscopy (SEM), contact angle measurements, X-ray photoelectron spectroscopy (XPS), and electron spectroscopy for chemical analysis (ESCA). Cells were seeded upon the different membranes, and cellular adhesion was analyzed qualitatively and quantitatively using fluorescence labeling and a hemocytometer, respectively. PTMem exhibited higher surface energies and the incorporation of reactive functional groups. NTP altered the surface topography and chemistry of PTFE membranes, as seen through SEM, XPS and ESCA, with partial defluorination and polymer chain breakage. Fluorescence labeling indicated significantly higher cell populations on PTMem relative to its untreated counterparts (NTMem). The results of this study support the potential applicability of allyl alcohol NTP treatment for polymeric biomaterials such as PTFE—to increase cellular adhesion for use as dental barrier membranes.

Publisher

MDPI AG

Subject

General Materials Science

Link

https://www.mdpi.com/1996-1944/16/20/6633/pdf

Reference75 articles.

1. Guided bone regeneration: Materials and biological mechanisms revisited;Elgali;Eur. J. Oral. Sci.,2017

2. Dimensional ridge alterations following tooth extraction. An experimental study in the dog;Araujo;J. Clin. Periodontol.,2005

3. Extraction site reconstruction for alveolar ridge preservation. Part 1: Rationale and materials selection;Bartee;J. Oral. Implant.,2001

4. Strategies for management of single-tooth extraction sites in aesthetic implant therapy;Sclar;J. Oral. Maxillofac. Surg.,2004

5. Modeling and remodeling of human extraction sockets;Trombelli;J. Clin. Periodontol.,2008