A Systematic Overview of Eudragit® Based Copolymer for Smart Healthcare

Author:

Nikam Aniket1,Sahoo Priya Ranjan23ORCID,Musale Shubham4,Pagar Roshani R.4,Paiva-Santos Ana Cláudia56ORCID,Giram Prabhanjan Shridhar47ORCID

Affiliation:

1. Department of Pharmaceutical Chemistry, Dr. D. Y. Patil Institute of Pharmaceutical Sciences and Research, Pimpri, Pune 411018, India

2. Department of Chemistry, University of Delhi, Delhi 110007, India

3. Department of Chemistry, University at Buffalo, The State University of New York, Amherst, NY 14260, USA

4. Department of Pharmaceutics, Dr. D. Y. Patil Institute of Pharmaceutical Sciences and Research, Pimpri, Pune 411018, India

5. Department of Pharmaceutical Technology, Faculty of Pharmacy of the University of Coimbra, 3004-531 Coimbra, Portugal

6. REQUIMTE/LAQV, Group of Pharmaceutical Technology, Faculty of Pharmacy of the University of Coimbra, 3004-531 Coimbra, Portugal

7. Department of Pharmaceutical Sciences, University at Buffalo, The State University of New York, Buffalo, NY 14214, USA

Abstract

Eudragit, synthesized by radical polymerization, is used for enteric coating, precise temporal release, and targeting the entire gastrointestinal system. Evonik Healthcare Germany offers different grades of Eudragit. The ratio of methacrylic acid to its methacrylate-based monomers used in the polymerization reaction defines the final product’s characteristics and consequently its potential range of applications. Since 1953, these polymers have been made to use in a wide range of healthcare applications around the world. In this review, we reviewed the “known of knowns and known of unknowns” about Eudragit, from molecule to material design, its characterization, and its applications in healthcare.

Publisher

MDPI AG

Subject

Pharmaceutical Science

Reference81 articles.

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