Abstract
Carbazole derivatives have gained a lot of attention in medicinal chemistry over the last few decades due to their wide range of biological and pharmacological properties, including antibacterial, antitumor, antioxidant, and anti-inflammatory activities. The therapeutic potential of natural, semi-synthetic or synthetic carbazole-containing molecules has expanded considerably owing to their role in the pathogenesis and development of diabetes. Several studies have demonstrated the ability of carbazole derivatives to reduce oxidative stress, block adrenergic hyperactivation, prevent damage to pancreatic cells and modulate carbohydrate metabolism. In this survey, we summarize the latest advances in the synthetic and natural carbazole-containing compounds involved in diabetes pathways.
Subject
Fluid Flow and Transfer Processes,Computer Science Applications,Process Chemistry and Technology,General Engineering,Instrumentation,General Materials Science
Reference78 articles.
1. Hyperglycemic Crises in Adult Patients with Diabetes;Kitabchi;Diabetes Care,2009
2. Postprandial Hyperglycaemia and Alpha-Glucosidase Inhibitors;Baron;Diabetes Res Clin Pract.,1998
3. Effect of the Postprandial State on Nontraditional Risk Factors;Lebovitz;Am. J. Cardiol.,2001
4. Epidemiology of Diabetes and Diabetes-Related Complications;Deshpande;Phys. Ther.,2008
5. Metabolic Syndrome X: A Comprehensive Review of the Pathophysiology and Recommended Therapy;J. Med.,2001
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