Research on a New Intelligent and Rapid Screening Method for Depression Risk in Young People Based on Eye Tracking Technology

Author:

Tao Zhanbo12,Sun Ningxia3,Yuan Zhen4ORCID,Chen Zeyuan2,Liu Jiakang5,Wang Chen5,Li Shuwu5,Ma Xiaowen5,Ji Bin6,Li Kai25

Affiliation:

1. Police Sports Department, Zhejiang Police College, Hangzhou 310053, China

2. Joint Laboratory of Police Health Smart Surveillance, Zhejiang Police College, Hangzhou 310053, China

3. Department of Reproductive Medicine, Second Affiliated Hospital of Naval Medical University, Shanghai 200003, China

4. Centre for Cognitive and Brain Sciences, University of Macau, Macau SAR 999078, China

5. Zhejiang-Japan Digital Diagnosis and Treatment and Equipment of Integrated Traditional Chinese Medicine and Western Medicine for Major Brain Diseases Joint Laboratory, Zhejiang Chinese Medical University, Hangzhou 310053, China

6. Department of Radiopharmacy and Molecular Imaging, School of Pharmacy, Fudan University, Shanghai 200032, China

Abstract

Depression is a prevalent mental disorder, with young people being particularly vulnerable to it. Therefore, we propose a new intelligent and rapid screening method for depression risk in young people based on eye tracking technology. We hypothesized that the “emotional perception of eye movement” could characterize defects in emotional perception, recognition, processing, and regulation in young people at high risk for depression. Based on this hypothesis, we designed the “eye movement emotional perception evaluation paradigm” and extracted digital biomarkers that could objectively and accurately evaluate “facial feature perception” and “facial emotional perception” characteristics of young people at high risk of depression. Using stepwise regression analysis, we identified seven digital biomarkers that could characterize emotional perception, recognition, processing, and regulation deficiencies in young people at high risk for depression. The combined effectiveness of an early warning can reach 0.974. Our proposed technique for rapid screening has significant advantages, including high speed, high early warning efficiency, low cost, and high intelligence. This new method provides a new approach to help effectively screen high-risk individuals for depression.

Funder

Province Key Research and Development Program of Zhejiang

Publisher

MDPI AG

Subject

General Neuroscience

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