Biliary and Vascular Complications after Liver Transplantation–From Diagnosis to Treatment

Author:

Gheorghe Gina12,Diaconu Camelia134ORCID,Bungau Simona5ORCID,Bacalbasa Nicolae14,Motas Natalia67,Ionescu Vlad-Alexandru12

Affiliation:

1. Faculty of Medicine, University of Medicine and Pharmacy Carol Davila Bucharest, 050474 Bucharest, Romania

2. Gastroenterology Department, Clinical Emergency Hospital of Bucharest, 105402 Bucharest, Romania

3. Internal Medicine Department, Clinical Emergency Hospital of Bucharest, 105402 Bucharest, Romania

4. Department of Visceral Surgery, Center of Excellence in Translational Medicine “Fundeni” Clinical Institute, 022328 Bucharest, Romania

5. Department of Pharmacy, Faculty of Medicine and Pharmacy, University of Oradea, 410028 Oradea, Romania

6. Institute of Oncology “Profesor Doctor Alexandru Trestioreanu” Bucharest, 022328 Bucharest, Romania

7. Department of Thoracic Surgery, University of Medicine and Pharmacy Carol Davila Bucharest, 050474 Bucharest, Romania

Abstract

The last decades have brought impressive advances in liver transplantation. As a result, there was a notable rise in the number of liver transplants globally. Advances in surgical techniques, immunosuppressive therapies and radiologically guided treatments have led to an improvement in the prognosis of these patients. However, the risk of complications remains significant, and the management of liver transplant patients requires multidisciplinary teams. The most frequent and severe complications are biliary and vascular complications. Compared to vascular complications, biliary complications have higher incidence rates but a better prognosis. The early diagnosis and selection of the optimal treatment are crucial to avoid the loss of the graft and even the death of the patient. The development of minimally invasive techniques prevents surgical reinterventions with their associated risks. Liver retransplantation remains the last therapeutic solution for graft dysfunction, one of the main problems, in this case, being the low number of donors.

Funder

University of Oradea, Oradea, Romania

Publisher

MDPI AG

Subject

General Medicine

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