Antithrombotics from the Sea: Polysaccharides and Beyond

Author:

Carvalhal Francisca,Cristelo Ricardo,Resende Diana,Pinto Madalena,Sousa Emília,Correia-da-Silva MartaORCID

Abstract

Marine organisms exhibit some advantages as a renewable source of potential drugs, far beyond chemotherapics. Particularly, the number of marine natural products with antithrombotic activity has increased in the last few years, and reports show a wide diversity in scaffolds, beyond the polysaccharide framework. While there are several reviews highlighting the anticoagulant and antithrombotic activities of marine-derived sulfated polysaccharides, reports including other molecules are sparse. Therefore, the present paper provides an update of the recent progress in marine-derived sulfated polysaccharides and quotes other scaffolds that are being considered for investigation due to their antithrombotic effect.

Publisher

MDPI AG

Subject

Drug Discovery,Pharmacology, Toxicology and Pharmaceutics (miscellaneous),Pharmaceutical Science

Reference165 articles.

1. The Top 10 Causes of Deathhttps://www.who.int/news-room/fact-sheets/detail/the-top-10-causes-of-death

2. Cardiovascular Diseases (cvds)https://www.who.int/news-room/fact-sheets/detail/cardiovascular-diseases-(cvds)

3. Heparin: Past, Present, and Future

4. Therapeutic Use of Heparin beyond Anticoagulation

5. Heparin Inhibition of Selectin-Mediated Interactions during the Hematogenous Phase of Carcinoma Metastasis: Rationale for Clinical Studies in Humans

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