Multiple Faces of the Glioblastoma Microenvironment

Author:

Șovrea Alina Simona,Boșca Bianca,Melincovici Carmen StancaORCID,Constantin Anne-Marie,Crintea Andreea,Mărginean Mariana,Dronca Eleonora,Jianu Mihaela Elena,Suflețel Rada,Gonciar Diana,Bungărdean Maria,Crivii Carmen-BiancaORCID

Abstract

The tumor microenvironment is a highly dynamic accumulation of resident and infiltrating tumor cells, responsible for growth and invasion. The authors focused on the leading-edge concepts regarding the glioblastoma microenvironment. Due to the fact that the modern trend in the research and treatment of glioblastoma is represented by multiple approaches that target not only the primary tumor but also the neighboring tissue, the study of the microenvironment in the peritumoral tissue is an appealing direction for current and future therapies.

Publisher

MDPI AG

Subject

Inorganic Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Computer Science Applications,Spectroscopy,Molecular Biology,General Medicine,Catalysis

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