State of the Art and Challenges in Epilepsy—A Narrative Review

Author:

Manole Aida1,Sirbu Carmen23ORCID,Mititelu Mihaela45ORCID,Vasiliu Octavian6,Lorusso Lorenzo7ORCID,Sirbu Octavian28,Ionita Radu Florentina910

Affiliation:

1. Department of Neurology, ‘Dr. Carol Davila’ Central Military Emergency University Hospital, 010242 Bucharest, Romania

2. Clinical Neurosciences Department, University of Medicine and Pharmacy “Carol Davila” Bucharest, 050474 Bucharest, Romania

3. Centre for Cognitive Research in Neuropsychiatric Pathology (Neuropsy-Cog), Department of Neurology, Faculty of Medicine, “Victor Babeș” University of Medicine and Pharmacy, 300041 Timișoara, Romania

4. Nuclear Medicine Department, ‘Dr. Carol Davila’ Central Military Emergency University Hospital, 010242 Bucharest, Romania

5. Department No.8, University of Medicine and Pharmacy “Carol Davila” Bucharest, 050474 Bucharest, Romania

6. Department of Psychiatry, ‘Dr. Carol Davila’ Central Military Emergency University Hospital, 010242, Bucharest, Romania

7. Neurology Unit—Neuroscience Dept. A.S.S.T.Lecco, Merate Hospital, 23807 Merate, Italy

8. Department of Neurosurgery, ‘Dr. Carol Davila’ Central Military Emergency University Hospital, 010242 Bucharest, Romania

9. Department of Gastroenterology, ‘Dr. Carol Davila’ Central Military Emergency University Hospital, 010825 Bucharest, Romania

10. Department of Gastroenterology, “Carol Davila” University of Medicine and Pharmacy, 020021 Bucharest, Romania

Abstract

Epilepsy is a common condition worldwide, with approximately 50 million people suffering from it. A single seizure does not mean epilepsy; almost 10% of the population can have a seizure during their lifetime. In particular, there are many other central nervous system disorders other than epilepsy in which seizures occur, either transiently or as a comorbid condition. The impact of seizures and epilepsy is, therefore, widespread and easily underestimated. It is estimated that about 70% of patients with epilepsy could be seizure-free if correctly diagnosed and treated. However, for patients with epilepsy, quality of life is influenced not only by seizure control but also by antiepileptic drug-adverse reactions, access to education, mood, employment, and transportation.

Funder

University of Medicine and Pharmacy Carol Davila through the in-stitutional program Publish not Perish

Publisher

MDPI AG

Subject

Medicine (miscellaneous)

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