Abstract
Echinops spinosissimus Turra subsp. bovei (Asteraceae) is a medicinal plant in western Algeria. Traditionally, roots and inflorescences are employed as hypertensive agents and in the treatment of hemorrhoids. The current study evaluates the chemical composition, antioxidant, antimicrobial, and wound-healing properties of the root methanolic extract from E. spinosissimus subsp. bovei. The content of total phenolics, flavonoids, and tannins was determined. In addition, the phenolic profile was typified. The studied plant extract resulted in being primarily composed of Apigenin, Kaempferol, and their derivatives. The total phenolic content was equal to 95.31 ± 2.90 mg GAE/g DW, while the number of flavonoids and condensed tannins was 16.01 ± 0.16 mg CE/g DW and 8.30 ± 0.65 mg CE/g DW, respectively. The methanolic extract was found to exhibit antioxidant activity towards the DPPH radical, with an IC50 of 7.99 ± 0.28 mg/mL and a TAC of 30.30 ± 0.54 mg AAE/g DW, as well as an antibacterial effect, especially against P. aeruginosa. No significant wound-healing property was observed, even though the histopathological observations showed enhanced wound-healing quality. According to our evidence, E. spinosissimus could represent a source of phytochemicals with potential beneficial effects for human health in terms of antioxidant and antibiotic properties, although further investigations on this species are needed.
Subject
Plant Science,Ecology,Ecology, Evolution, Behavior and Systematics
Reference70 articles.
1. Everywhere but Antarctica: Using a supertree to understand the diversity and distribution of the Compositae;Funk;Biol. Skr.,2005
2. African Plant Database (2020, August 15). Version 3.4.0. Conservatoire et Jardin botaniques de la Ville de Genève and South African National Biodiversity Institute, Pretoria. Available online: http://www.ville-ge.ch/musinfo/bd/cjb/africa/details.php?Langue=fr&id=137404.
3. The Plant List (2020, August 16). Version 1.1. Jardins Botaniques Royaux de Kew et le Jardin Botanique du Missouri. Available online: http://www.theplantlist.org/.
4. Quezel, P., and Santa, S. (1963). Nouvelle Flore de l’Algérie et des Régions Désertiques Méridionale, CNRS Editions. Tome II.
5. Antifeedant and toxicity effects of thiophenes from four Echinops species against the Formosan subterranean termite, Coptotermes formosanus;Fokialakis;Pest Manag. Sci.,2006
Cited by
2 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献