On the Potential of Relational Databases for the Detection of Clusters of Infection and Antibiotic Resistance Patterns
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Published:2023-04-19
Issue:4
Volume:12
Page:784
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ISSN:2079-6382
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Container-title:Antibiotics
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language:en
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Short-container-title:Antibiotics
Author:
Gelfusa Michela1ORCID, Murari Andrea23, Ludovici Gian Marco1ORCID, Franchi Cristiano1, Gelfusa Claudio1, Malizia Andrea4ORCID, Gaudio Pasqualino1ORCID, Farinelli Giovanni5, Panella Giacinto5, Gargiulo Carla5, Casinelli Katia5
Affiliation:
1. Department of Industrial Engineering, University of Rome “Tor Vergata”, 00133 Rome, Italy 2. Consorzio RFX (CNR, ENEA, INFN), University of Padua, 35127 Padua, Italy 3. Istituto per la Scienza e la Tecnologia dei Plasmi, CNR, 35100 Padua, Italy 4. Department of Biomedicine and Prevention, University of Rome “Tor Vergata”, 00133 Rome, Italy 5. ASL and Fabrizio Spaziani, Frosinone Hospital, 03100 Frosinone, Italy
Abstract
In recent years, several bacterial strains have acquired significant antibiotic resistance and can, therefore, become difficult to contain. To counteract such trends, relational databases can be a powerful tool for supporting the decision-making process. The case of Klebsiella pneumoniae diffusion in a central region of Italy was analyzed as a case study. A specific relational database is shown to provide very detailed and timely information about the spatial–temporal diffusion of the contagion, together with a clear assessment of the multidrug resistance of the strains. The analysis is particularized for both internal and external patients. Tools such as the one proposed can, therefore, be considered important elements in the identification of infection hotspots, a key ingredient of any strategy to reduce the diffusion of an infectious disease at the community level and in hospitals. These types of tools are also very valuable in the decision-making process related to antibiotic prescription and to the management of stockpiles. The application of this processing technology to viral diseases such as COVID-19 is under investigation.
Subject
Pharmacology (medical),Infectious Diseases,Microbiology (medical),General Pharmacology, Toxicology and Pharmaceutics,Biochemistry,Microbiology
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