Community Antibiotic Consumption in Cyprus for the Period 2015 to 2022

Author:

Mitsoura Eirini12,Kopsidas Ioannis13ORCID,Charalambous Pambos4,Papazisis Georgios2ORCID,Raikos Nikolaos5ORCID,Pana Zoi Dorothea1

Affiliation:

1. Medical School, European University of Cyprus, 2404 Nicosia, Cyprus

2. Department of Clinical Pharmacology & Clinical Research Unit, School of Medicine, Aristotle University, 54124 Thessaloniki, Greece

3. Center for Clinical Epidemiology and Outcomes Research (CLEO), 15451 Athens, Greece

4. IAS Sinopsis Ltd., 1071 Nicosia, Cyprus

5. Department of Forensic Science and Toxicology & Clinical Research Unit, School of Medicine Aristotle University, 54124 Thessaloniki, Greece

Abstract

Background: Cyprus currently reports to ESAC-Net the total consumption of antimicrobials, without distinguishing between hospital and community-based antibiotic use. As a result, these data can only provide generalized insights into antimicrobial trends in the country. Aim: This study is a first attempt to retrospectively analyze community antibiotic consumption in Cyprus for the period of 2015 to 2022. Material and Methods: Data on community antimicrobial consumption between 2015 and 2022 were extracted from Pharmatrack’s database. Orally administered dispensed antibiotics were categorized under the J01 group of the WHO Anatomical Therapeutic Chemical (ATC) classification and by the WHO’s AWaRe classification of antibiotics. Antibiotic consumption was calculated in both packages consumed and per 1000 inhabitants, overall, by year of consumption and districts. Results: During the period of 2015–2022, there was variability in the mean outpatient antibiotic consumption per 1000 inhabitants among the five districts in Cyprus. Community consumption increased by 38% throughout the study period. Additionally, a decrease of 3% in the consumption of WHO ‘Access’ antibiotics was observed, accompanied with a concurrent increase of 3% in the ‘Watch’ group. Specifically, in 2022 the WHO ‘Access’ group consumption in the Cypriot community was 48%, significantly lower than the WHO’s goal of 60% and the EU’s goal of 70% for ‘Access’ antibiotic consumption. Conclusions: Antibiotic consumption in the community of Cyprus between 2015 and 2022 demonstrated substantial variability among districts, with higher consumption in less populated areas. There was an increasing trend in community consumption over the years and a decreasing trend in the percentage of ‘Access’ antibiotics prescribed.

Publisher

MDPI AG

Subject

Pharmacology (medical),Infectious Diseases,Microbiology (medical),General Pharmacology, Toxicology and Pharmaceutics,Biochemistry,Microbiology

Reference25 articles.

1. European Centre for Disease Prevention and Control (2022). Antimicrobial Resistance Surveillance in Europe 2022: 2020 Data, World Health Organization Publications Office.

2. (2023, September 25). A European One Health Action Plan against Antimicrobial Resistance (AMR). Available online: https://health.ec.europa.eu/system/files/2020-01/amr_2017_action-plan_0.pdf.

3. (2023, November 25). 35,000 Annual Deaths from Antimicrobial Resistance in the EU/EEA. Available online: https://www.ecdc.europa.eu/en/news-events/eaad-2022-launch.

4. The Impact of Coronavirus Disease 2019 (COVID-19) on Healthcare-Associated Infections;Baker;Clin. Infect. Dis.,2022

5. Flare of the Silent Pandemic in the Era of the COVID-19 Pandemic: Obstacles and Opportunities;Rayan;World J. Clin. Cases,2023

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