Essential Oils: Chemistry and Pharmacological Activities

Author:

de Sousa Damião P.1ORCID,Damasceno Renan Oliveira S.2,Amorati Riccardo3ORCID,Elshabrawy Hatem A.4ORCID,de Castro Ricardo D.5ORCID,Bezerra Daniel P.6ORCID,Nunes Vitória Regina V.1,Gomes Rebeca C.1,Lima Tamires C.7

Affiliation:

1. Department of Pharmaceutical Sciences, Federal University of Paraiba, João Pessoa 58051-900, Brazil

2. Department of Physiology and Pharmacology, Center of Biosciences, Federal University of Pernambuco, Recife 50670-901, Brazil

3. Department of Chemistry “G. Ciamician”, University of Bologna, Via Gobetti 83, 40129 Bologna, Italy

4. Department of Molecular and Cellular Biology, College of Osteopathic Medicine, Sam Houston State University, Conroe, TX 77304, USA

5. Department of Clinical and Social Dentistry, Federal University of Paraíba, João Pessoa 58051-970, Brazil

6. Instituto Gonçalo Moniz, Fundação Oswaldo Cruz (IGM-FIOCRUZ/BA), Salvador 40296-710, Brazil

7. Department of Pharmacy, Federal University of Sergipe, São Cristóvão 49100-000, Brazil

Abstract

In this review, we provide an overview of the current understanding of the main mechanisms of pharmacological action of essential oils and their components in various biological systems. A brief introduction on essential oil chemistry is presented to better understand the relationship of chemical aspects with the bioactivity of these products. Next, the antioxidant, anti-inflammatory, antitumor, and antimicrobial activities are discussed. The mechanisms of action against various types of viruses are also addressed. The data show that the multiplicity of pharmacological properties of essential oils occurs due to the chemical diversity in their composition and their ability to interfere with biological processes at cellular and multicellular levels via interaction with various biological targets. Therefore, these natural products can be a promising source for the development of new drugs.

Funder

Federal University of Paraíba

Publisher

MDPI AG

Subject

Molecular Biology,Biochemistry

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