Postoperative Weight Gain within Enhanced Recovery after Cardiac Surgery

Author:

Krüger Alexandra1,Flo Forner Anna2,Ender Jörg2,Janai Aniruddha2,Roufail Youssef3,Otto Wolfgang4,Meineri Massimiliano2,Zakhary Waseem Z. A.2

Affiliation:

1. Heart Center Leipzig, University of Leipzig, Strümpellstraße 39, 04289 Leipzig, Germany

2. Department of Anesthesiology and Intensive Care Medicine, Heart Center Leipzig, Strümpellstraße 39, 04289 Leipzig, Germany

3. Health Sciences, Faculty of Science, Waterloo Campus, Wilfrid Laurier University, Waterloo, ON N2L 3C5, Canada

4. Department of Cardiac Surgery, Heart Center Leipzig, Strümpellstraße 39, 04289 Leipzig, Germany

Abstract

Optimal fluid therapy during perioperative care as part of enhanced recovery after cardiac surgery (ERACS) should improve the outcome. Our objective was finding out the effects of fluid overload on outcome and mortality within a well-established ERACS program. All consecutive patients undergoing cardiac surgery between January 2020 and December 2021 were enrolled. According to ROC curve analysis, a cut-off of ≥7 kg (group M, n = 1198) and <7 kg (group L, n = 1015) was defined. A moderate correlation was shown between weight gain and fluid balance r = 0.4, and a simple linear regression was significant p < 0.0001, R2 = 0.16. Propensity score matching showed that increased weight gain was associated with a longer hospital length of stay (LOS) (L 8 [3] d vs. M 9 [6] d, p < 0.0001), an increased number of patients who received pRBCs (L 311 (36%) vs. M 429 (50%), p < 0.0001), and a higher incidence of postoperative acute kidney injury (AKI) (L 84 (9.8%) vs. M 165 (19.2%), p < 0.0001). Weight gain can easily represent fluid overload. Fluid overload after cardiac surgery is common and is associated with prolonged hospital LOS and increases the incidence of AKI.

Publisher

MDPI AG

Subject

Pharmacology (medical),General Pharmacology, Toxicology and Pharmaceutics

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