A Case of Paraneoplastic Anti-TIF1-γ Antibody-Positive Dermatomyositis Presenting with Generalized Edema and Associated with Aortic Aneurysm

Author:

Bennett Raven1,Bradley Katherine1,Salem Iman2,Weiner David3,Patel Dhrumil2,Cloutier Jeffrey4,Pace Nicole2,Barton Dorothea2

Affiliation:

1. Geisel School of Medicine at Dartmouth, Hanover, NH 03755, USA

2. Department of Dermatology Dartmouth-Hitchcock Medical Center, Lebanon, NH 03766, USA

3. Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA

4. Department of Pathology and Laboratory Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, NH 03756, USA

Abstract

Dermatomyositis (DM) is a rare autoimmune inflammatory disease characterized by pathognomonic skin findings, often accompanied by myositis beginning with proximal weakness [...]

Publisher

MDPI AG

Subject

General Medicine

Reference32 articles.

1. Dermatomyositis presenting with severe subcutaneous edema: Five additional cases and review of the literature;Milisenda;Semin. Arthritis Rheum.,2014

2. Myositis autoantibodies and clinical phenotypes;Ghirardello;Autoimmun. Highlights,2014

3. Most patients with cancer-associated dermatomyositis have antibodies to nuclear matrix protein NXP-2 or transcription intermediary factor 1γ;Fiorentino;Arthritis Rheum.,2013

4. Dermatomyosite œdémateuse sévère [Severe edematous dermatomyositis];Goussot;Ann. Dermatol. Venereol.,2016

5. Subcutaneous oedema as a presenting feature of polymyositis/dermatomyositis: A poor prognostic indicator?;Dunkley;Grand Rounds,2007

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