Dual-Energy CT in Cardiothoracic Imaging: Current Developments

Author:

Alizadeh Leona S.123,Vogl Thomas J.1ORCID,Waldeck Stephan S.34,Overhoff Daniel35ORCID,D’Angelo Tommaso6ORCID,Martin Simon S.12,Yel Ibrahim12ORCID,Gruenewald Leon D.12,Koch Vitali12ORCID,Fulisch Florian3ORCID,Booz Christian12

Affiliation:

1. Department of Diagnostic and Interventional Radiology, University Hospital Frankfurt, 60590 Frankfurt, Germany

2. Division of Experimental Imaging, Department of Diagnostic and Interventional Radiology, University Hospital Frankfurt, 60590 Frankfurt, Germany

3. Department of Diagnostic and Interventional Radiology, Bundeswehrzentralkrankenhaus Koblenz, 56072 Koblenz, Germany

4. Department of Diagnostic and Interventional Radiology, University Hospital Mainz, 55131 Mainz, Germany

5. Department of Diagnostic and Interventional Radiology, University Hospital Mannheim, 68167 Mannheim, Germany

6. Diagnostic and Interventional Radiology Unit, Department of Biomedical Sciences and Morphological and Functional Imaging, “G. Martino” University Hospital Messina, 98124 Messina, Italy

Abstract

This article describes the technical principles and clinical applications of dual-energy computed tomography (DECT) in the context of cardiothoracic imaging with a focus on current developments and techniques. Since the introduction of DECT, different vendors developed distinct hard and software approaches for generating multi-energy datasets and multiple DECT applications that were developed and clinically investigated for different fields of interest. Benefits for various clinical settings, such as oncology, trauma and emergency radiology, as well as musculoskeletal and cardiovascular imaging, were recently reported in the literature. State-of-the-art applications, such as virtual monoenergetic imaging (VMI), material decomposition, perfused blood volume imaging, virtual non-contrast imaging (VNC), plaque removal, and virtual non-calcium (VNCa) imaging, can significantly improve cardiothoracic CT image workflows and have a high potential for improvement of diagnostic accuracy and patient safety.

Publisher

MDPI AG

Subject

Clinical Biochemistry

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