Radiomics and Magnetic Resonance Imaging of Rectal Cancer: From Engineering to Clinical Practice

Author:

Coppola FrancescaORCID,Giannini ValentinaORCID,Gabelloni Michela,Panic Jovana,Defeudis Arianna,Lo Monaco SilviaORCID,Cattabriga Arrigo,Cocozza Maria Adriana,Pastore Luigi VincenzoORCID,Polici MichelaORCID,Caruso DamianoORCID,Laghi AndreaORCID,Regge Daniele,Neri EmanueleORCID,Golfieri RitaORCID,Faggioni LorenzoORCID

Abstract

While cross-sectional imaging has seen continuous progress and plays an undiscussed pivotal role in the diagnostic management and treatment planning of patients with rectal cancer, a largely unmet need remains for improved staging accuracy, assessment of treatment response and prediction of individual patient outcome. Moreover, the increasing availability of target therapies has called for developing reliable diagnostic tools for identifying potential responders and optimizing overall treatment strategy on a personalized basis. Radiomics has emerged as a promising, still fully evolving research topic, which could harness the power of modern computer technology to generate quantitative information from imaging datasets based on advanced data-driven biomathematical models, potentially providing an added value to conventional imaging for improved patient management. The present study aimed to illustrate the contribution that current radiomics methods applied to magnetic resonance imaging can offer to managing patients with rectal cancer.

Publisher

MDPI AG

Subject

Clinical Biochemistry

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