Affiliation:
1. Faculty of Medicine, University of Novi Sad, 21000 Novi Sad, Serbia
2. Institute for Cardiovascular Diseases of Vojvodina, 21204 Sremska Kamenica, Serbia
Abstract
Background: as a relatively high number of ST-segment elevation myocardial infarction (STEMI) patients develop major adverse cardiovascular events (MACE) following percutaneous coronary intervention (PCI), our aim was to determine the significance, and possible predictive value of QRS complex width and ST-segment elevation. Methods: our patient sample included 200 PCI-treated STEMI patients, which were divided into two groups based on the following duration of symptoms: (I) less than 6 h, and (II) 6 to 12 h. For every patient, an ECG was performed at six different time points, patients were followed for up to six years for the occurrence of MACE. Results: the mean age was 60.6 ± 11.39 years, and 142 (71%) were male. The 6–12 h group had significantly wider QRS complex, higher ST-segment elevation, lower prevalence of ST-segment resolution as well as MACE prevalence (p < 0.05). ECG parameters, QRS width, and magnitude of ST-segment elevation were proved to be independent significant predictors of MACE in all measured time points (p < 0.05). Even after controlling for biomarkers of myocardial injury, these ECG parameters remained statistically significant predictors of MACE (p < 0.05). Conclusion: our study highlights that wider QRS complex and a more pronounced ST-segment elevation are associated with longer total ischemic time and higher risk of long-term MACE.
Reference41 articles.
1. Triglyceride-Glucose Body Mass Index Predicts Prognosis in Patients with ST-Elevation Myocardial Infarction;Liu;Sci. Rep.,2024
2. He, J., Kong, L., An, D., Chen, B., Zhao, C., Li, Z., Yang, F., Dong, J., Wei, L., and Shan, P. (2024). Prognostic Value of Segmental Strain After ST-Elevation Myocardial Infarction: Insights from the EARLY Assessment of MYOcardial Tissue Characteristics by Cardiac Magnetic Resonance (EARLY-MYO-CMR) Study. J. Magn. Reson. Imaging.
3. Characterization of the Average Daily Ischemic and Bleeding Risk After Primary PCI for STEMI;Giustino;J. Am. Coll. Cardiol.,2017
4. The Burden of Major Adverse Cardiac Events in Patients with Coronary Artery Disease;Tsai;BMC Cardiovasc. Disord,2017
5. Major Adverse Cardiovascular Events: An Inevitable Outcome of ST-Elevation Myocardial Infarction? A Literature Review;Poudel;Cureus,2019