SARS-CoV-2 Infection: What Is Currently Known about Homocysteine Involvement?
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Published:2022-12-21
Issue:1
Volume:13
Page:10
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ISSN:2075-4418
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Container-title:Diagnostics
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language:en
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Short-container-title:Diagnostics
Author:
Filip NinaORCID, Cojocaru ElenaORCID, Badulescu Oana Viola, Clim Andreea, Pinzariu Alin ConstantinORCID, Bordeianu Gabriela, Jehac Alina Elena, Iancu Cristina Elena, Filip Cristiana, Maranduca Minela AidaORCID, Sova Ivona Andreea, Serban Ionela Lacramioara
Abstract
Since December 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread rapidly throughout the world causing health, social and economic instability. The severity and prognosis of patients with SARS-CoV-2 infection are associated with the presence of comorbidities such as cardiovascular disease, hypertension, chronic lung disease, cerebrovascular disease, diabetes, chronic kidney disease, and malignancy. Thrombosis is one of the most serious complications that can occur in patients with COVID-19. Homocysteine is a non-proteinogenic α-amino acid considered a potential marker of thrombotic diseases. Our review aims to provide an updated analysis of the data on the involvement of homocysteine in COVID-19 to highlight the correlation of this amino acid with disease severity and the possible mechanisms by which it intervenes.
Subject
Clinical Biochemistry
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