Exploring the Challenges of Using Minimal Invasive Surgery to Treat Stress Urinary Incontinence: Insights from a Retrospective Case-Control Study

Author:

Hașegan Adrian1ORCID,Mihai Ionela1,Teodoru Cosmin Adrian1,Matacuta Ioana Bogdan1,Dura Horațiu1,Todor Samuel Bogdan1,Ichim Cristian1,Tanasescu Denisa1,Grigore Nicolae1,Bolca Ciprian Nicolae2ORCID,Mohor Cosmin Ioan1,Mohor Călin Ilie1,Bacalbașa Nicolae3,Bratu Dan Georgian1ORCID,Boicean Adrian1ORCID

Affiliation:

1. Faculty of Medicine, Lucian Blaga University of Sibiu, 550169 Sibiu, Romania

2. Surgery Department, Universite de Sherbrooke, Sherbrooke, QC J1K 2R1, Canada

3. Surgery Department, University of Medicine and Pharmacy “Carol Davila” Bucharest, 020021 Bucharest, Romania

Abstract

Stress urinary incontinence (SUI) is a significant global health issue that particularly affects females, leads to notable societal and economic challenges and significantly affects the quality of life. This study focuses on the comparative analysis of two established surgical interventions, tension-free vaginal tape (TVT) and transobturator tape (TOT), at a single center and applied to 455 women suffering from SUI, with a mean follow-up period of 102 ± 30 months for TVT and 80.4 ± 13 months for TOT. Our findings indicate that, in comparison to TVT, the TOT procedure demonstrates fewer early and late post-operative complications in patient outcomes (1.41% vs. 17.64% and; 5.66% vs. 12.74%, both respectively). However, the TVT procedure shows a modestly favorable outcome in the risk of recurrence of SUI, compared to TOT (0% vs. 3.7%); the TOT procedure has also proven to be more effective in alleviating of urgency symptoms, although not at a statistically significant level (p = 0.072). Univariable and multivariable analysis of factors that predict late complications showed that only obesity can predict a worse outcome [OR]: 1.125 CI 95%: 1.105–1.533, p = 0.037), when adjustments are made for symptoms presented before surgery and procedure type. While both methods are safe and effective, the choice between them should be based on the specific characteristics of each case.

Funder

Lucian Blaga University of Sibiu (Knowledge Transfer Center) & Hasso Plattner Foundation research

Ministry of Research, Innovation, and Digitization

Publisher

MDPI AG

Subject

Clinical Biochemistry

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