Immature Sacrococcygeal Teratoma: A Case Report and Extensive Review of the Literature

Author:

Varlas Valentin Nicolae12ORCID,Cloțea Eliza Maria2,Varlas Roxana Georgiana2,Pop Anca13ORCID,Peneș Ovidiu14ORCID,Crețoiu Dragoș56ORCID,Dima Vlad7ORCID,Bălănescu Laura18

Affiliation:

1. Faculty of Medicine, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, Romania

2. Department of Obstetrics and Gynecology, Filantropia Clinical Hospital, 011132 Bucharest, Romania

3. Department of Clinical Laboratory, Food Safety, “Carol Davila” University of Medicine and Pharmacy, 6 Traian Vuia Street, 020945 Bucharest, Romania

4. Department of Intensive Care, University Clinical Hospital, “Carol Davila” University of Medicine and Pharmacy, 37 Dionisie Lupu St., 020021 Bucharest, Romania

5. Fetal Medicine Excellence Research Center, Alessandrescu-Rusescu National Institute for Mother and Child Health, 020395 Bucharest, Romania

6. Department of Genetics, Carol Davila University of Medicine and Pharmacy, 8 Eroii Sanitari Blvd., 050474 Bucharest, Romania

7. Department of Neonatology, Filantropia Clinical Hospital, 011132 Bucharest, Romania

8. Department of Pediatric Surgery, Children Emergency Hospital “Grigore Alexandrescu”, 011743 Bucharest, Romania

Abstract

Immature sacrococcygeal teratoma represents a histological form with rapid tumor growth, a risk of premature birth, an enhanced rate of complications, an increased risk of recurrence, and a higher mortality rate than the mature type. Thus, prenatal diagnosis of immature forms would significantly improve the prognosis of these cases. To this end, we performed an extensive literature review on the diagnosis, therapeutic management, and follow-up of immature teratomas. Regarding this medical conduct, we also presented our case. In conclusion, the early identification of immature sacrococcygeal teratomas with or without other associated structural abnormalities and their correct therapeutic approach are basic principles for a favorable evolution of these cases.

Publisher

MDPI AG

Subject

Clinical Biochemistry

Reference85 articles.

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