A Scoring Method to Prioritize Fecal Occult Blood Testing as a First Step in Colorectal Cancer Screening in Resource-Limited Settings

Author:

Bărbulescu Linda-Nicoleta12,Rădulescu Virginia-Maria34ORCID,Mogoantă Stelian-Ștefăniță56,Bărbulescu Lucian-Florentin7ORCID,Kamal Constantin8,Radu Mirela8,Cismaru Liana9

Affiliation:

1. Doctoral School, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania

2. Cabinet Medical Dr. Profir I. Mirela SRL, 200145 Craiova, Romania

3. Department of Medical Informatics and Biostatistics, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania

4. Department of Automation and Electronics, University of Craiova, 200585 Craiova, Romania

5. Department of Surgery, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania

6. Department III of Surgery, University Emergency County Hospital, 200642 Craiova, Romania

7. Department of Computers and Information Technology, University of Craiova, 200585 Craiova, Romania

8. Department of Family Medicine, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania

9. Department of Pediatrics, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania

Abstract

This study aims to develop a scoring method that can be used by primary care physicians from remote areas or resource-limited settings to estimate the need for fecal occult blood testing (FOBT) as a first step in colorectal cancer screening. This method relies on several modifiable risk factors that can influence a positive FOBT, an indication of the presence of colorectal polyps, or even colorectal cancer. The scoring method considers, besides the age and gender of the patient, the body mass index (BMI), smoking status, and the diagnoses of diabetes mellitus (type 2 diabetes), dyslipidemia, and hypertension. It does not need any paraclinical exams, which is an advantage when access or material resources are limited. The retrospective study was spread over forty-three months, respectively, from October 2019 to April 2023, and included 112 patients. The score that we designed is a numerical value between 0 and 7. The values between 0 and 3 represent a smaller risk of a positive FOBT (9.68%), values 4 and 5 represent a medium risk (14.75%), while values 6 and 7 represent a greater risk (40%). Using this score, a physician can determine if a patient has a greater risk and recommend it to prioritize taking a FOB test.

Funder

University of Medicine and Pharmacy of Craiova, Romania

Publisher

MDPI AG

Subject

Clinical Biochemistry

Reference42 articles.

1. Decrease in Incidence of Colorectal Cancer Among Individuals 50 Years or Older After Recommendations for Population-based Screening;Murphy;Clin. Gastroenterol. Hepatol. Off. Clin. Pract. J. Am. Gastroenterol. Assoc.,2017

2. Romanian National Institute of Public Health (2023, June 12). Cancer Analysis. May 2022, (In Romanian).

3. Romanian National Institute of Public Health (2023, June 12). General Mortality, (In Romanian).

4. Lorenzovici, N., Dulf, E.-H., Mocan, T., and Mocan, L. (2021). Artificial Intelligence in Colorectal Cancer Diagnosis Using Clinical Data: Non-Invasive Approach. Diagnostics, 11.

5. Burnett, B., Zhou, S.-M., Brophy, S., Davies, P., Ellis, P., Kennedy, J., Bandyopadhyay, A., Parker, M., and Lyons, R.A. (2023). Machine Learning in Colorectal Cancer Risk Prediction from Routinely Collected Data: A Review. Diagnostics, 13.

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3