Attention TurkerNeXt: Investigations into Bipolar Disorder Detection Using OCT Images

Author:

Arslan Sermal1,Kaya Mehmet Kaan1ORCID,Tasci Burak2ORCID,Kaya Suheda3ORCID,Tasci Gulay3ORCID,Ozsoy Filiz4ORCID,Dogan Sengul5ORCID,Tuncer Turker5ORCID

Affiliation:

1. Universal Eye Clinic, 23119 Elazig, Turkey

2. Vocational School of Technical Sciences, Firat University, 23119 Elazig, Turkey

3. Department of Psychiatry, Elazig Fethi Sekin City Hospital, 23100 Elazig, Turkey

4. Department of Psychiatry, School of Medicine, Tokat Gaziosmanpasa University, 60100 Tokat, Turkey

5. Department of Digital Forensics Engineering, College of Technology, Firat University, 23119 Elazig, Turkey

Abstract

Background and Aim: In the era of deep learning, numerous models have emerged in the literature and various application domains. Transformer architectures, particularly, have gained popularity in deep learning, with diverse transformer-based computer vision algorithms. Attention convolutional neural networks (CNNs) have been introduced to enhance image classification capabilities. In this context, we propose a novel attention convolutional model with the primary objective of detecting bipolar disorder using optical coherence tomography (OCT) images. Materials and Methods: To facilitate our study, we curated a unique OCT image dataset, initially comprising two distinct cases. For the development of an automated OCT image detection system, we introduce a new attention convolutional neural network named “TurkerNeXt”. This proposed Attention TurkerNeXt encompasses four key modules: (i) the patchify stem block, (ii) the Attention TurkerNeXt block, (iii) the patchify downsampling block, and (iv) the output block. In line with the swin transformer, we employed a patchify operation in this study. The design of the attention block, Attention TurkerNeXt, draws inspiration from ConvNeXt, with an added shortcut operation to mitigate the vanishing gradient problem. The overall architecture is influenced by ResNet18. Results: The dataset comprises two distinctive cases: (i) top to bottom and (ii) left to right. Each case contains 987 training and 328 test images. Our newly proposed Attention TurkerNeXt achieved 100% test and validation accuracies for both cases. Conclusions: We curated a novel OCT dataset and introduced a new CNN, named TurkerNeXt in this research. Based on the research findings and classification results, our proposed TurkerNeXt model demonstrated excellent classification performance. This investigation distinctly underscores the potential of OCT images as a biomarker for bipolar disorder.

Publisher

MDPI AG

Subject

Clinical Biochemistry

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