Recent Advances in Ultrasound Breast Imaging: From Industry to Clinical Practice

Author:

Catalano Orlando1,Fusco Roberta2,De Muzio Federica3,Simonetti Igino4,Palumbo Pierpaolo56ORCID,Bruno Federico56ORCID,Borgheresi Alessandra78,Agostini Andrea78,Gabelloni Michela9ORCID,Varelli Carlo1,Barile Antonio10ORCID,Giovagnoni Andrea78,Gandolfo Nicoletta11,Miele Vittorio612ORCID,Granata Vincenza4ORCID

Affiliation:

1. Department of Radiology, Istituto Diagnostico Varelli, 80126 Naples, Italy

2. Medical Oncology Division, Igea SpA, 80013 Naples, Italy

3. Department of Medicine and Health Sciences “V. Tiberio”, University of Molise, 86100 Campobasso, Italy

4. Division of Radiology, “Istituto Nazionale Tumori IRCCS Fondazione Pascale-IRCCS di Napoli”, 80131 Naples, Italy

5. Department of Diagnostic Imaging, Area of Cardiovascular and Interventional Imaging, Abruzzo Health Unit 1, 67100 L’Aquila, Italy

6. Italian Society of Medical and Interventional Radiology (SIRM), SIRM Foundation, 20122 Milan, Italy

7. Department of Clinical, Special and Dental Sciences, University Politecnica delle Marche, 60126 Ancona, Italy

8. Department of Radiology, University Hospital “Azienda Ospedaliera Universitaria delle Marche”, 60126 Ancona, Italy

9. Department of Translational Research, Diagnostic and Interventional Radiology, University of Pisa, 56126 Pisa, Italy

10. Department of Applied Clinical Sciences and Biotechnology, University of L’Aquila, 67100 L’Aquila, Italy

11. Diagnostic Imaging Department, Villa Scassi Hospital-ASL 3, Corso Scassi 1, 16149 Genoa, Italy

12. Department of Emergency Radiology, Careggi University Hospital, 50134 Florence, Italy

Abstract

Breast ultrasound (US) has undergone dramatic technological improvement through recent decades, moving from a low spatial resolution, grayscale-limited technique to a highly performing, multiparametric modality. In this review, we first focus on the spectrum of technical tools that have become commercially available, including new microvasculature imaging modalities, high-frequency transducers, extended field-of-view scanning, elastography, contrast-enhanced US, MicroPure, 3D US, automated US, S-Detect, nomograms, images fusion, and virtual navigation. In the subsequent section, we discuss the broadened current application of US in breast clinical scenarios, distinguishing among primary US, complementary US, and second-look US. Finally, we mention the still ongoing limitations and the challenging aspects of breast US.

Publisher

MDPI AG

Subject

Clinical Biochemistry

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