Abstract
The serum level of diamine oxidase (DAO) reflects the integrity and maturation of the small intestinal mucosa. This measure is important in diagnosing various diseases, including chronic urticaria tachyphylaxis, multiple organ dysfunction syndrome, preterm abortion, and migraine. This review aimed to summarize the findings of previous studies on the changes in DAO levels in diverse diseases and the application of this enzyme in the clinical setting, as well as the roles of this enzyme under physiological and pathological conditions. The advances in the mechanism and clinical application of DAO presented in this review will contribute to a better understanding of this enzyme and open up new and broader perspectives for future basic research and clinical applications.
Funder
Scientific Foundation of Zhejiang Provincial Ministry of Education
Natural Science Foundation of Zhejiang Province
Foundation of Zhejiang Provincial Administration of Traditional Chinese Medicine
Subject
Physical and Theoretical Chemistry,Catalysis,General Environmental Science
Reference106 articles.
1. Intestinal Diamine Oxidases and Enteral-Induced Histaminosis: Studies on Three Prognostic Variables in an Epidemiological Model;Sattler;J. Neural Transm. Suppl.,1990
2. Diamine oxidase and catalase are expressed in the same cells but are present in different subcellular compartments in porcine kidney;Schwelberger;Inflamm. Res.,1999
3. Histamine and histamine intolerance;Maintz;Am. J. Clin. Nutr.,2007
4. Purification and characterization of diamine oxidase from porcine kidney and intestine;Schwelberger;Biochim. Biophys. Acta,1997
5. Correlation of intestinal mucosal injury with serum diamine oxidase;Zhou;Zhonghua Er Ke Za Zhi,2006
Cited by
5 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献